The Benefits of Vaccinating With the First Available COVID-19 Coronavirus Vaccine

Bartsch, Sarah M.; O’Shea, Kelly J; Wedlock, Patrick T.; Strych, Ulrich; Ferguson, Marie C.; Bottazzi, María Elena; Randall, Samuel; Siegmund, Sheryl S.; Cox, Sarah N; Hotez, Peter J.; Lee, Bruce Y.

doi:10.1016/j.amepre.2021.01.001

Cited by 35 publications

(51 citation statements)

References 12 publications

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“…This percentage is not high enough to achieve herd immunity through the vaccination program. 5 This acceptance rate is lower than that in other countries, such as China (91.3%), France (58.9%), the US (56.9%), and Russia (54.9%). Furthermore, the acceptance rate is lower than the rate reported in a previous study in Japan (65.7%) that was conducted in September 2020.…”

Section: Discussionmentioning

confidence: 77%

“…4 To reach herd immunity, most citizens need to be vaccinated. 5 Vaccination intentions are recognized as the most important issue in the rollout of vaccination programs. 6 However, Japan is known for its lack of public trust in vaccines 7 because negative campaigns against the vaccination-highlighting scandals and severe adverse effects, for instance-have increased hesitation concerning some vaccinations over the past several decades.…”

Section: Introductionmentioning

confidence: 99%

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Gender differences in the determinants of willingness to get the COVID-19 vaccine among the working-age population in Japan

Ishimaru¹,

Okawara²,

Ando³

et al. 2021

Preprint

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Many factors are related to vaccination intentions. However, gender differences in the determinants of intention to get the coronavirus disease 2019 (COVID-19) vaccine have not been fully investigated. This study examined gender differences in the determinants of willingness to get the COVID-19 vaccine among the working-age population in Japan. We conducted a cross-sectional study of Japanese citizens aged 20-65 years using an online self-administered questionnaire in December 2020. Logistic regression analysis was performed. Among 27,036 participants (13,814 men and 13,222 women), the percentage who were willing to get the COVID-19 vaccine was lower among women than among men (33.0% vs. 41.8%). Age and education level showed a gender gap regarding the association with willingness to get the COVID-19 vaccine: men who were older or had a higher level of education were more willing to get the vaccine, whereas women aged 30-49 years and those with a higher level of education showed a relatively low willingness to get the vaccine. For both men and women, marriage, higher annual household income, underlying disease, current smoking, vaccination for influenza during the current season, and fear of COVID-19 transmission were linked to a higher likelihood of being willing to get the COVID-19 vaccine. These findings give important insight into identifying target groups in need of intervention regarding COVID-19 vaccination, especially among women. Providing education about COVID-19 and influenza vaccination in the workplace may be an effective strategy to increase COVID-19 vaccine uptake.

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Section: Discussionmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Gender differences in the determinants of willingness to get the COVID-19 vaccine among the working-age population in Japan

Ishimaru¹,

Okawara²,

Ando³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Due to the rapid development of those vaccines in 2020 and their conditional approval, they were the subject of anti-vaccine campaigns and vaccination hesitancy among populations. Official clinical trials showed that these two most predominantly used COVID-19 vaccines have acceptable safety profiles [57,58].…”

Section: Discussionmentioning

confidence: 99%

Self-Reported Adverse Events of COVID-19 Vaccines in Polish Healthcare Workers and Medical Students. Cross-Sectional Study and Pooled Analysis of CoVaST Project Results in Central Europe

Dziedzic

Riad

Attia

et al. 2021

JCM

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Background: Optimization of COVID-19 vaccination rate among healthcare personnel is of utmost priority to secure provision of uninterrupted care and to protect the most vulnerable patients. This study, as part of the global CoVaST project, aimed to assess the occurrence of short-term adverse events (SRAEs) of two most administered COVID-19 vaccines, mRNA-based (Pfizer-BioNTech and Moderna) and viral vector-based (AstraZeneca) in healthcare sector workers (HWs). Methods: A cross-sectional survey-based study was carried out for the first time among 317 Polish healthcare sector personnel and medical students using a validated and pre-tested questionnaire. The online questionnaire included 25 pre-tested, validated questions concerning demographic data, medical parameters, COVID-19-related anamneses, and local or systemic reactions (reactogenicity) associated with COVID-19 vaccination. Descriptive statistics, inferential tests and binary logistic regression were performed. Results: Out of the 247 participating HWs, 79.8% were females, and 77.5% received mRNA-based vaccines, while 24.5% received a viral vector-based vaccine. Cumulatively, 78.9% and 60.7% of the participants reported at least one local and one systemic SRAE respectively, following their COVID-19 first or second dose of vaccine. A wide array of SRAEs was observed, while pain at injection site (76.9%) was the most common local SRAE, and fatigue (46.2%), headache (37.7%), muscle pain (31.6%) were the most common systemic SRAEs. The vast proportion of local (35.2%) and systemic (44.8%) SRAEs subsided up to 1 day after inoculation with both types of vaccines. The mRNA-based vaccine versions seem to cause higher prevalence of local SRAEs, mainly pain within injection site (81.3% vs. 71.7%; p = 0.435), while the viral vector-based vaccine was linked with increased incidents of mild systemic side effects (76.7% vs. 55.3%; p = 0.004) after both doses. Pooled analysis revealed uniform results while comparing the prevalence of SRAEs in HWs as recipients in four central European countries (OR = 2.38; 95% CI = 2.03–2.79). Conclusions: The study confirmed the safety of commonly administered vaccines against COVID-19, which were associated with mild, self-resolving adverse events. No major vaccine-related incidents were reported which would affect every day functioning, significantly. The younger age group (below 29 y.o.) were associated with an increased risk of adverse events generally. The results enhanced current data regarding COVID-19 vaccination active surveillance in selected occupational groups.

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“…With a higher number of infections, the effectiveness of the preparations is not satisfactory [ 1 ]. Other studies show that new vaccines should not be waited more efficiently as this may cause the pandemic to spread more widely [ 2 ]. Doctors in Poland and many other countries belong to the so-called the zero group that is the first to receive the vaccine.…”

Section: Introductionmentioning

confidence: 99%

Subjective Feelings of Polish Doctors after Receiving the COVID-19 Vaccine

Zdziarski

Landowski

Zabielska

et al. 2021

IJERPH

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The COVID-19 pandemic has caused enormous confusion around the world in our daily existence. The security measures taken, such as physical distance, wearing a mask, quarantine or closing shopping malls, and even isolating large groups of the population, did not contribute to the complete overcoming of the problem. Information on the positive results of research into the COVID-19 vaccine and, finally, its administration offered hope that the pandemic would be overcome. The undertaken problem of research concerning the subjective analysis of the feelings of doctors in Poland after receiving the COVID-19 vaccine shows an important area of the medical world, which is directly responsible for their own health and the patients entrusted to them. In addition, 149 people participated in the study (8–13 February 2021), including 57% of women and 43% of men. The minimum and maximum age of the respondents are 26 and 69 years old. Furthermore, 85% of respondents took two doses of the vaccine and 15% took one. The authorial questionnaire was completed by the participants in the study online in February 2021. The results obtained indicate that the COVID-19 vaccine generates hope for stopping the pandemic. In addition, 96% of research participants think so. Doctors in middle and mature age are the most optimistic, while the youngest ones are less optimistic. In addition, 57% of respondents do not worry about side effects after taking the vaccine. Fear at the time of vaccination was experienced by over 9% of doctors. The most frequently reported post-vaccination reactions are injection site pain, fatigue and headache. Increased temperature occurred in older female respondents. From a psychosocial perspective, men are more likely to fear being infected personally with the virus, and women are more likely to be infected with their loved ones. The presented subjective assessment presents the physicians’ view captured at the moment in terms of existential and emotional. The presented feelings of the research participants reflect their personal satisfaction, responsibility for their own health, care for their relatives and patients.

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The Benefits of Vaccinating With the First Available COVID-19 Coronavirus Vaccine

Cited by 35 publications

References 12 publications

Gender differences in the determinants of willingness to get the COVID-19 vaccine among the working-age population in Japan

Gender differences in the determinants of willingness to get the COVID-19 vaccine among the working-age population in Japan

Self-Reported Adverse Events of COVID-19 Vaccines in Polish Healthcare Workers and Medical Students. Cross-Sectional Study and Pooled Analysis of CoVaST Project Results in Central Europe

Subjective Feelings of Polish Doctors after Receiving the COVID-19 Vaccine

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