The Benefits of Dietary Fiber Intake on Reducing the Risk of Cancer: An Umbrella Review of Meta-analyses

McRae, Marc P.

doi:10.1016/j.jcm.2017.12.001

Cited by 54 publications

(35 citation statements)

References 43 publications

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“…Fiber: A review of all published meta-analyses was performed on the association between dietary fiber and colorectal cancer conclude that the high consumption of fiber may benefit from a reduction in the incidence of developing colorectal cancer [67]. High-fiber content has many roles, including diluting and binding potential carcinogens as well as reducing transit time [68,69].…”

Section: Discussionmentioning

confidence: 99%

Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review

et al. 2020

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Background: Between 30 and 50% of colon tumors have mutations in the Kirsten-ras (KRAS) gene, which have a large nutritional attributable risk. Despite its high frequency in colorectal cancer (CRC), data to support specific associations between KRAS mutations in CRC and diet are sparse. Here, we conducted a systematic review to summarize the current epidemiological evidence on the association between various dietary factors and KRAS mutations. Methods: PubMed, Science Direct, and Cochrane databases were searched for relevant studies published until December 31, 2019, using inclusion and exclusion criteria in accordance with PRISMA guidelines. We analyzed the studies to find associations between nutritional factors and CRC tumors with KRAS mutations in humans. Results: We identified 28 relevant studies to include in this systematic review. In-depth analyses showed unclear associations between nutritional factors and KRAS mutations in CRC. Most epidemiological studies in the same nutrient or food often reported conflicting and/or inconclusive findings, whereas for some dietary factors, the results were homogeneous. Conclusions: Further research using a more robust prospective cohort study is needed to lend more credence to the epidemiological associations found between KRAS mutations and dietary factors.

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Section: Discussionmentioning

confidence: 99%

Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review

et al. 2020

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“…The importance of dietary fibre in the prevention of colorectal cancer remains controversial. However, studies conducted on large population samples showed that high intakes of dietary fibre, especially from grains, cereals, and whole grain cereal foods are associated with reduced risks of colorectal [23,28,39,40,41,42] and gastric cancer [33,41]. Many other studies strengthen the evidence for dietary fibre protective role in the prevention of colon and/or rectum cancer [43,44,45,46,47].…”

Section: Introductionmentioning

confidence: 99%

How Important are Cereals and Cereal Products in the Average Polish Diet?

et al. 2019

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The main aim of this study was to identify the food sources of energy and 28 nutrients from cereals and cereal products in the average Polish diet based on data from a nationally representative sample of the Polish population attending in 2016 Household Budget Survey (i.e., 36,886 households). The contribution of energy and nutrients from cereals and cereal products were compared with reference values. The detailded analysis included five main groups and nine sub-groups of cereal food category. Our findings indicated that cereals and cereal products contributed 30.4% of total dietary energy supply, providing a significant percentage of six nutrients to the average Polish diet (i.e., 64.1% of manganese, 51% of carbohydrates, 48.5% of dietary fibre, 34.1% of iron, 33.6% of folate, and 31.3% of copper). Supply at the level of 20–30% was observed for protein, thiamin, phosphorus and zinc, and at 10–20% for polyunsaturated fatty acids (PUFA), sodium, potassium, calcium, riboflavin, niacin, and vitamin B6. For other nutrients i.e., total fat, saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), cholesterol, iodine, vitamins: A, D, B12, and C, the share of cereals and cereal products contribution was below 10%. Cereals and cereal products were the major food category in meeting the reference values for the Polish population in case of manganese, carbohydrates (approximately100%), and sodium (50%). The reference values was reached at the level of 30–40% for dietary fibre, protein, iron, copper, zinc, phosphorus and thiamin, and 20–30% for energy, magnesium, folate, niacin, riboflavin, vitamins B6 and E. For such nutrients as total fat, SFA, and potassium, the fulfillment of the reference values amounted to 10–20%. Our results document the importance of cereals and cereal products in the Polish diet, which should be emphasized from a nutritional and health point of view.

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“…Furthermore, dietary factors [7] may affect the risk of esophageal cancer. Previous studies suggested that vitamins intake [8,9], fiber intake [10], folate intake [11,12], could decrease the development of esophageal cancer. Intakes of bioactive compounds from various plant sources also reduced the risk of cancer [13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

The association between dietary protein intake and esophageal cancer risk: a meta-analysis

et al. 2020

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Correspondence: Hua Wang (wang hua@yeah.net) Several papers studied dietary protein intake as a potential influence factor for esophageal cancer, but their findings were inconsistent. Thus, this meta-analysis was performed to identify the effect of protein intake on esophageal cancer risk. Potential case-control studies or cohort studies from the databases of Embase, Web of Science and PubMed were searched. The strength of association was quantified by pooling odds ratio (OR) and 95% confidence interval (CI). In total, 11 articles involving 2537 cases and 11432 participants were included in this meta-analysis. As a result, dietary protein intake had non-significant association on esophageal cancer risk overall (pooled OR = 1.11, 95% CI = 0.88-1.40). Meanwhile, we obtained consistent results in the subgroups analyses by study design, protein type, geographic locations and number of cases. Interestingly, dietary protein intake could significantly increase the risk of esophageal squamous cell carcinoma (pooled OR = 1.29, 95% CI = 1.02-1.62), instead of other disease type. To sum up, dietary protein intake had no significant association with esophageal cancer risk in the overall analysis; but, protein intake may be associated with the risk of esophageal squamous cell carcinoma. While some limitations existed in the present paper, more studies with large sample size are warranted to further confirm this result.Statistical analysis was conducted by Stata 12.0 (StataCorp, College Station, U.S.A.). Pooled ORs with their 95% CIs was calculated using the independent OR and its 95% CI in each individual study [21]. Stratified analyses were

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The Benefits of Dietary Fiber Intake on Reducing the Risk of Cancer: An Umbrella Review of Meta-analyses

Abstract: This review suggests that those consuming the highest amounts of dietary fiber may benefit from a reduction in the incidence of developing colorectal cancer, and there also appears to be a small reduction in the incidence of breast cancer.

Cited by 54 publications

References 43 publications

Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review

Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review

How Important are Cereals and Cereal Products in the Average Polish Diet?

The association between dietary protein intake and esophageal cancer risk: a meta-analysis

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