The Benefits and Scope of Surface Plasmon Resonance-based Biosensors in Food Analysis

McWhirter, A.D.; Wahlström, Lennart

doi:10.1039/9781847558220-00333

Cited by 9 publications

(4 citation statements)

References 13 publications

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“…Surface plasmon resonance (SPR) spectroscopy has become a valuable tool for enabling real-time, label-free detection of biomolecular interactions in both singular − and multiplexed formats. − This technique exploits the sensitivity of surface plasmons to changes in the refractive index (RI) occurring at a metal (typically gold or silver)−dielectric interface and has found utility in applications ranging from fundamental studies of the thermodynamics and kinetics of biomolecular interactions − to medical diagnostics, ,− environmental monitoring, ,, and food safety. − …”

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confidence: 99%

Multispectral Thin Film Biosensing and Quantitative Imaging Using 3D Plasmonic Crystals

et al. 2009

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This work provides plasmonic crystal platforms for quantitative imaging mode biosensing and multispectral immunoassays, establishing and validating both the optical and equilibrium bases for their operation. We investigated the distance-dependent refractive index sensitivity of full 3D plasmonic crystals to thin polymeric films formed using layer by layer (LbL) assembly of polyelectrolytes as a model system. LbL was also used to determine the preferred gold thickness and plasmonic crystal design rules (nanowell diameter and periodicity) for improved thin-film sensitivity, and full 3D finite-difference time-domain (FDTD) calculations were used to quantitatively model and confirm the experimentally observed thin film sensitivities. The integrated multispectral response of the crystals increases approximately linearly with film thickness for values <70 nm, which enables the use of molecular rulers with known thicknesses (such as self-assembled monolayers of alkanethiols on gold) to calibrate these optics for quantitative detection and speciation of surface binding events in a multiplexed imaging format. The utility of these sensors and multispectral analysis for applications in quantitative biosensing was further demonstrated by measuring the equilibrium response curve of an antibody/antigen pair (rabbit antigoat IgG/goat IgG) at increasing antigen concentrations. Fitting the integrated response to a Langmuir isotherm yielded a calculated binding constant on the order of approximately 10(7) M(-1), which is in agreement with the affinity constants reported in the literature for anti-IgG/IgG binding pairs and provides intrinsic detection limits of approximately 400 pM for such unamplified assays.

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confidence: 99%

Multispectral Thin Film Biosensing and Quantitative Imaging Using 3D Plasmonic Crystals

et al. 2009

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“…Food safety and food quality control in food industry SPR sensors have also been employed in food analysis [9]. Key features of the SPR sensor are (1) its gold standard sensitivity.…”

Section: Biological Protein Interaction In Life Sciencementioning

confidence: 99%

Surface Plasmon Biosensor Platform for Food Industry

Pechprasarn

Ittipornnuson

Jungpanich

et al. 2019

AMM

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Surface plasmon resonance (SPR) based biosensor is a gold standard optical sensor for biological protein interaction in life science. In this paper, we firstly discuss how the SPR based sensor can give unique advantages over other sensing techniques for food safety and food quality control in food industry. We discuss the differences in sample preparation process for the SPR system and other screening methods and point out that the SPR can reduce the food screen quality control cost and time. A brief review of food analysis that has been tested under SPR system. Key requirements for building up a surface plasmon resonance based sensor for food industry especially in Thailand are highlighted. An SPR based sensor has been recently developed and constructed based on the requirements. We also discuss practical issues and how to possibly get around them.

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“…It has been also found that many SPR -based data processing techniques have been introduced. The study of [18] discussed that the most common commercially available SPR based bio sensors are bia-core 2000 and 3000 systems. The SPR based bio sensors are fortified with a four flow-cell fluidic system where one flow cell is used as a reference to subtract possible nonspecific signal.…”

Section: The Proposed Solutionmentioning

confidence: 99%

A Thorough Insight to Techniques for Performance Evaluation in Biological Sensors

Meti

Sangam

2016

IJECE

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The biological sensor has played a significant and contributory role in the area of medical science and healthcare industry. Owing to critical healthcare usage, it is essential that such type of sensors should be highly robust, sustainable under the adverse condition and highly fault tolerant against any forms of possible system failure in future. A massive amount of research work has been done in the area of the sensor network. However, works done in biological sensors are quite less in number. Hence, this manuscript highlights all the significant research work towards the line of discussion for evaluating the effective in the techniques for performance evaluation of biological sensor. The study finally explores the problems and discusses it under research gap. Finally, the manuscript gives highlights of the future direction of the work to solve the research gap explored from the proposed review of the existing system.

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The Benefits and Scope of Surface Plasmon Resonance-based Biosensors in Food Analysis

Cited by 9 publications

References 13 publications

Multispectral Thin Film Biosensing and Quantitative Imaging Using 3D Plasmonic Crystals

Multispectral Thin Film Biosensing and Quantitative Imaging Using 3D Plasmonic Crystals

Surface Plasmon Biosensor Platform for Food Industry

A Thorough Insight to Techniques for Performance Evaluation in Biological Sensors

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