The behaviour of Tenax as food simulant in the migration of polymer additives from food contact materials by means of gas chromatography/mass spectrometry and PARAFAC

Abstract

 Migration of polymer additives from food contact materials into Tenax was studied  PARAFAC enabled the unequivocal identification in the presence of coeluting compounds  Some of the m/z ratios of the coeluting interferents were shared with the analytes  Tenax as a suitable food simulant is questioned considering its adsorption capability  BP and DiBP have migrated from PVC film and from PP coffee capsules

Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry

“…DEHP as well as other phthalates have also been found in Italian espresso [ 4 , 14 ], with higher concentrations when brewed in a plastic capsule versus by a moka pot (plastic-free) 14 ]. Furthermore, plasticizers including BP were evident in plastic capsule coffee [ 24 ], which is consistent with the results of our study. In our study, neither DBP nor BP were detected in French press coffee, suggesting that the content of ECs in coffee may be contingent on the types of material making contact with the coffee.…”

“…In our study, neither DBP nor BP were detected in French press coffee, suggesting that the content of ECs in coffee may be contingent on the types of material making contact with the coffee. Plasticizers can leach from food packing, particularly from plastic containers [ 25 ] including polyvinyl chloride film (food wrap) and polypropylene capsules [ 24 ]. However, even non-plastic food containers such as paper and cardboard can leach ECs [ 26 ] which may explain the BPA and BPF detected in the few French press coffee samples.…”

Targeting dopamine receptor D2 as a novel therapeutic strategy in endometrial cancer

“…Historically, modulation of the dopaminergic pathway has primarily focused on neurologic diseases or antipsychotic therapy. However, a growing body of literature reveals increased mRNA and protein expression of the G protein-coupled dopamine receptor D2 (DRD2) in many tumors including breast, colon, pancreas, prostate, glioblastoma, lymphoma, and endometrial cancer [10][11][12][13][14]. Knockdown of DRD2 or inhibition with pharmacologic antagonists in glioblastoma, pituitary tumors, pancreatic and breast cancer cells leads to inhibition of proliferation and migration as well as anti-tumorigenic effects in number of different xenograft mouse models [11,[13][14][15][16].…”

Estrogenic activity of capsule coffee using the VM7Luc4E2 assay

“…As no estrogenic chemicals were detected in the blanks run through the coffee brewing machine, it is apparent that contamination occurs within the capsule. The capsules are typically composed of polypropylene which has been shown to leach estrogenic chemicals in food products ( Yang et al, 2011 , Rubio et al, 2019 ). High temperatures also significantly increase the rate of migration of estrogenic chemicals from plastic ( Le et al, 2008 , Cooper et al, 2011 ), due in part to the non-covalent bond between certain plasticizers to plastic ( Rowdhwal and Chen, 2018 ).…”