“…Finally, 16 studies with 1,739 patients and 3,630 controls met the inclusion and exclusion criteria (Bruenig et al., 2016; Dai et al., 2017; Dretsch et al., 2016; Guo et al., 2018, 2019; Heon‐Jeong et al., 2006; Hori et al., 2020; Jin et al., 2019; Li et al., 2016; Lyoo et al., 2011; Pivac et al., 2012; Qi et al., 2020; Valente et al., 2011; Young et al., 2018; Zhang et al., 2006, 2014). There were four studies in Caucasian populations (Bruenig et al., 2016; Pivac et al., 2012; Young et al., 2018; Zhang et al., 2006), nine studies in Asian populations (Dai et al., 2017; Guo et al., 2018, 2019; Heon‐Jeong et al., 2006; Hori et al., 2020; Jin et al., 2019; Li et al., 2016; Lyoo et al., 2011; Qi et al., 2020), and three studies in mixed populations (Dretsch et al., 2016; Valente et al., 2011; Zhang et al., 2014). Five studies used the polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) method, while the rest used real‐time PCR, TaqMan, SnaPShot, Sequencer platform, and Illumina methods.…”