The Bantu Prostate: A Study of Prostatic Disease in Central Africa

Houston, W.

doi:10.1016/s0022-5347(17)62700-9

Cited by 7 publications

(3 citation statements)

References 14 publications

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“…A short life expectancy, a diet high in fiber and low in fat, and liver disease seemed to protect the rural Bantu man from getting prostate cancer. 9,10 Herein we report on the prevalence of HGPIN and prostate cancer; in Dibombari, a rural district of Cameroon.…”

Section: Introductionmentioning

confidence: 99%

High-grade intra-epithelial neoplasia and prostate cancer in Dibombari, Cameroon

Angwafo

Zaher

Befidi-Mengue

et al. 2003

Prostate Cancer Prostatic Dis

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High-grade prostatic intra-epithelial neoplasia (HGPIN) occurs a decade earlier in men of African descent in the US and Brazil, compared to white men. Prostate cancer incidence and mortality is worse in the African-American than in US white men. Sub-Saharan Africa was thought to be a low incidence area. This disparity has been attributed to lifestyle factors such as diet. We report the results of prostatic biopsies, from an ongoing national prostate cancer survey. One hundred and eleven men aged 40 y and over were recruited for medical interview (AUA symptom score), prostate specific antigen (PSA) assay and digital rectal examination (DRE). Between six and 10 cores of random digitally guided needle biopsies were performed on 24 subjects that had either suspicious prostates on digital rectal examination þ / or PSA 4 ng/ml. All lesions of the prostate were described on routine histopathology. The Gleason score and proportion of tissue involved with cancer, was determined. Eight men had benign prostatic hyperplasia (BPH), six had cancer, another six had low grade intra-epithelial neoplasia, two had HGPIN, there was one case of BPH and chronic prostatitis and one case of chronic prostatitis only. The cancer patients were aged 58 -75 y (mean 66.93 y). Gleason scores ranged from 5 to 9, there was one score of 3. Cancer made up 20 -80% tissue samples. HGPIN was found in two cases (mean age 58 y). Significant prostate cancer and the pre-cancerous lesion HGPIN exist in Dibombari, Cameroon. The purported low incidence of prostate cancer may reflect cultural and economic barriers to health care.

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Section: Introductionmentioning

confidence: 99%

High-grade intra-epithelial neoplasia and prostate cancer in Dibombari, Cameroon

Angwafo

Zaher

Befidi-Mengue

et al. 2003

Prostate Cancer Prostatic Dis

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“…Although it was popularly believed several decades ago that benign prostatic hypertrophy was uncommon in the indigenous Africans [1,2], there is now abundant evidence that prostatic disease is as common in the Negro race as in Caucasians [3][4][5][6][7][8][9][10], Today, the most commonly applied method of prostatectomy in Europe and America is the transurethral resection of the prostate [11,12]. However, for reasons related to skill, availability of instruments and limitation of operating opportunities, the suprapubic ap proach is still the most popular method of prostatectomy in most parts of the developing world.…”

Section: Introduction Subjectsmentioning

confidence: 99%

Suprapubic Prostatectomy without Suprapubic Tube and without Bladder Irrigation

Esho¹,

Kuwong²,

Gbadamosi³

1989

Eur Urol

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“…Several decades ago, it was popularly believed that benign prostatic hypertrophy (BPH) was uncommon among the indigenous people of Africa [Walker and Barnes, 1922;Movsas, 1966;Bernes et al, 1967], There is now abundant evidence from various parts of Africa that prostatic disease is as common in the Negro race as in Caucasians [Kahle and Beacham, 1936;Houston, 1968;Amaku et al, 1971;Kambal, 1976;Anikwe, 1978;Esho and Obasanya, 1978;Awojobi et al, 1983]. Also common in the Negro race is the develop ment of inguinal hernias [Cole, 1965;Omo-Dare, 1966;Adesola, 1968;Chiedozi, 1980].…”

Section: Introductionmentioning

confidence: 99%