The Association of Red Cell Distribution Width with Glycated Hemoglobin among Healthy Adults without Diabetes Mellitus

Veeranna, Vikas; Zalawadiya, Sandip; Panaich, Sidakpal; Ramesh, Krithi; Afonso, Luís

doi:10.1159/000339225

Cited by 49 publications

(43 citation statements)

References 24 publications

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“…We are clearly in agreement with the mounting evidence for the various associations of RDW and adverse outcomes [3,4]. Its availability and inexpensiveness make it an attractive factor to consider in the risk stratification of patients.…”

supporting

confidence: 89%

Red Blood Cell Distribution Width Should Indeed Be Assessed with Other Inflammatory Markers in Daily Clinical Practice

Ephrem¹

2013

Cardiology

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supporting

confidence: 89%

Red Blood Cell Distribution Width Should Indeed Be Assessed with Other Inflammatory Markers in Daily Clinical Practice

Ephrem¹

2013

Cardiology

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“…Again in a study of V. Veranna et al examined RDW and HbA1C relation in a healthy adult. It was observed that in a healthy adult without DM, RDW is predicative of HbA1C disease development [17].…”

Section: Discussionmentioning

confidence: 99%

Correlation between red blood cell distrubition width and glycated hemoglobin in diabetic and nondiabetic patients

Dilara¹,

Hülya²,

Kilinc³

et al. 2016

Russ Open Med J

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Aim -Our aim in this study is evaluating the red blood cell distrubition width (RDW) and glycated hemoglobin (HbA1C) relation in nondiabetic and diabetic people who applied to our hospital and showing the usability in disease follow-up. Material and Methods -Main data of this research is the data of patients (diabetic and nondiabetic) who applied to internal diseases polyclinic between July 1, 2013 and November 31, 2014 and whose RDW, HbA1C, white blood cell, hemoglobin, and hematocrit were controlled. 82 diabetic and 32 nondiabetic patients were included in this study. Results -No statistically significant difference was observed between the diabetic and nondiabetic groups in age, male and female distribution and RDW. No statistically significant correlation was observed between RDW and age and HbA1C in order in the nondiabetic group. While a correlation which is statistically significant and in the same direction was determine between age and RDW among the diabetic group, a statistically significant correlation was not between HbA1C and RDW. Among all cases a correlation which is statistically meaningful and in the same direction was detected between age and RDW. But a statistically significant correlation was not found between HbA1C and RDW among all cases. Conclusion -According to the available results, no statistically significant correlation was determined between HbA1C and RDW in the nondiabetic patients, diabetic group or in total. But in order to provide more clearance, we believe that studies with more patients would be useful.

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“…The HbA1c concentration represents the average blood glucose level over the previous three months, is free of short-term fluctuations, and can be monitored long term and controlled according to individual circumstances to an appropriate level to reduce the risk of serious complications (2). Very recently, a relationship between the elevated red blood cell (RBC) distribution width (RDW) and higher HbA1c concentrations was found in a large cross-sectional study (3).…”

Section: Introductionmentioning

confidence: 99%

Association of the Elevated Red Blood Cell Distribution Width with the Risk of Developing Diabetes Mellitus

Li¹,

Lifang²

2016

Intern. Med.

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Objective The aim of this study was to determine whether elevated levels of RDW-coefficient of variation (CV) are associated with the development of diabetes mellitus (DM) in a population of healthy middle-and old-aged individuals. Method We conducted a retrospective cohort study. A total of 2,688 individuals (aged 49-66 years) without a DM diagnosis, impaired fasting glucose, or anemia at baseline were grouped according to the RDW-CV quartile, and the onset of DM during a 4-year period was recorded for each group. Results The correlation coefficients for the RDW-CV and waist circumference and for the RDW-CV and HbA1c were 0.114 and 0.133, respectively. The relative risks of future DM in RDW-CV quartiles II, III, and IV (high) compared with RDW-CV quartile I (low) were 1.9 [95% confidence interval (CI) 1.0-3.6, p=0.057], 1.6 (95% CI 0.8-3.0, p=0.157), and 2.2 (95% CI 1.2-4.0, p=0.015), respectively. After adjusting for sex, age, waist circumference, hemoglobin A1c, triglycerides, high density lipoprotein-cholesterol (HDL-C), and highsensitivity C-reactive protein , the multivariate relative risk for the highest vs. the lowest RDW-CV quartile was 1.8 (95% CI, 1.1-3.4, p=0.046). Conclusion These data indicate that an elevated RDW-CV is associated with an increased incidence of DM.

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The Association of Red Cell Distribution Width with Glycated Hemoglobin among Healthy Adults without Diabetes Mellitus

Cited by 49 publications

References 24 publications

Red Blood Cell Distribution Width Should Indeed Be Assessed with Other Inflammatory Markers in Daily Clinical Practice

Red Blood Cell Distribution Width Should Indeed Be Assessed with Other Inflammatory Markers in Daily Clinical Practice

Correlation between red blood cell distrubition width and glycated hemoglobin in diabetic and nondiabetic patients

Association of the Elevated Red Blood Cell Distribution Width with the Risk of Developing Diabetes Mellitus

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