The Association Between Suicide Attempts, Anxiety, and Childhood Maltreatment Among Adolescents and Young Adults With First Depressive Episodes

Chen, Hui; Li, Wen; Cao, Xia; Liu, Peiqu; Liu, Jiali; Chen, Xianliang; Luo, Chenyuli; Liang, Xiaoxi; Guo, Huijuan; Zhong, Shaoling; Wang, Xiaoping; Zhou, Jiansong

doi:10.3389/fpsyt.2021.745470

Cited by 9 publications

(9 citation statements)

References 62 publications

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“…The sample size was calculated using the formula, n = Z 2 p(1-p)/d 2 . n = number of sample size; Z = 95% confidence interval equal to 1.96; d = 0.05 (5%), marginal error; p = expected prevalence, equal to 0.315 according to a previous Chinese study [8]. This gave an estimate for a sample of 331 patients.…”

Section: Participantsmentioning

confidence: 99%

“…A meta-analysis found that the lifetime prevalence of suicide attempts was 31% and one year prevalence was 8% in MDD patients [7]. The prevalence of suicide attempts in adolescents and young adult MDD patients was from 31.5% to 43.7% in different studies [8,9]. However, in China, the suicide attempt rate of young adults with MDD is still not clear.…”

Section: Introductionmentioning

confidence: 99%

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Suicide attempt rate and the risk factors in young, first-episode and drug-naïve Chinese Han patients with major depressive disorder

Yue

et al. 2022

BMC Psychiatry

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Background: In recent years, the rates of suicide among young people have been increasing, and major depressive disorder (MDD) is regarded to be its main cause. Many factors such as thyroid dysfunction and metabolic abnormalities are thought to mediate this process, but the conclusions are inconsistent. This study investigated the rate of suicide attempts and associated risk factors among young, first-episode and drug-naïve Chinese Han patients with MDD.Methods: A total of 917 patients with MDD (aged 18 ~ 35 years) were recruited. Demographic and clinical data were collected and thyroid function, fasting blood glucose and lipid profiles were measured. The Hamilton Depression Rating Scale-17 items (HAMD-17), Hamilton Anxiety Rating Scale (HAMA), positive symptom subscale of Positive and Negative Syndrome Scale (PANSS) and clinical global impression of severity scale (CGI-S) were adopted to assess depression, anxiety, psychotic symptoms and disease severity respectively. Results:The rate of suicide attempts was 19.5% in young MDD patients. There were significant differences in age (p = 0.003), education level (p = 0.001), age of onset (p = 0.004) and disease duration (p = 0.001) between patients with and without suicide attempts. Compared with patients without suicide attempts, patients with suicide attempts had significantly higher scores on the HAMD-17, HAMA, PANSS positive symptom subscale and CGI-S (all p < 0.001). Patients with suicide attempts had significantly higher levels of TSH (p < 0.001), TgAb (p = 0.004), TPOAb (p < 0.001), TG (p = 0.016), TC (p < 0.001), LDL (p < 0.001), and fasting glucose (p < 0.001), but significantly lower levels of HDL (p < 0.001). Logistic regression analysis showed that marital status (OR = 0.

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Section: Participantsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Suicide attempt rate and the risk factors in young, first-episode and drug-naïve Chinese Han patients with major depressive disorder

Yue

et al. 2022

BMC Psychiatry

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“…This paradox might be partially explained, as previously mentioned, by the different methods used in suicides: male adolescents often die by suicide using firearms, whereas females use asphyxiation or hanging. In addition, females are more likely than males to die from poisoning or overdoses (Chen et al, 2021). Overall, females attempt suicide more often than men but use less lethal methods and report a lower rate of mortality (Chen et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

Suicides among Children and Adolescents in Paraguay: An 18-year National Exploratory Study (2004–2022)

Torales

Barrios

Tullo-Gómez

et al. 2023

Int J Soc Psychiatry

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Background: Suicide and suicide attempts are impacting events for patients and their relatives, and these behaviors are still taboo among adults and may be even more traumatic when involving children and adolescents. Aim: In this study we aimed to describe suicide rates among children and adolescents in Paraguay over the last decades as well as associated factors such as sociodemographic characteristics and methods used for suicide. Methods: This was an observational and exploratory study describing the frequency and characteristics of suicide among children and adolescents in Paraguay between 2004 and 2022. Official records of all deaths by suicide were reviewed, and statistical analyses were performed. In addition, an attempt was made to predict the number of suicides in the next 5 years using a mathematical model based on simple linear regression. Results: In the 18-year period observed, 940 suicides among children and adolescents were recorded. The mean age was 15.05 ± 1.8 years old. Of these, 51.17% were male, 74.6% were from urban areas, and 22.2% were from the Greater Asunción and Central Department of Paraguay. The most frequently used method of suicide was intentional self-inflicted injury by hanging, strangulation, or suffocation, which all represented 75.3% of the cases. Our mathematical modeling based on simple linear regression determined that the expected yearly number of national suicides in the pediatric population for the following years, from 2023 to 2027, will range between 72 and 81. Conclusion: This study is the first large national epidemiological report on the emerging issue of suicide among children and adolescents in Paraguay. It may be a relevant source of information for mental health professionals, health authorities, and decision makers to develop national prevention strategies and actions against suicide among youths.

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“…Nowadays, a lot of prior work has supported that childhood maltreatment is a robust predictor of suicide behaviours (Chen et al, 2021a;Grillault et al, 2022;Stagaki et al, 2022;Van Bentum et al, 2022). Childhood maltreatment is typically defined as any action of commission or omission by parents or other caregivers that brings direct or potential harm, which generally encompasses five core subtypes: physical abuse, emotional abuse, sexual abuse, physical neglect and emotional neglect (Bernstein et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Specific effects of five subtypes of childhood maltreatment on suicide behaviours in Chinese adolescents: the moderating effect of sex and residence

Peng

Cheng

Rong

et al. 2023

Epidemiol Psychiatr Sci

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Aims Although childhood maltreatment has been widely supported to be a robust predictor of suicide behaviours, the effects of different childhood maltreatment subtypes remain controversial and inconclusive. Moreover, whether the effects differ by sex in urban and rural adolescents is still unknown. This study aimed to quantify the associations between five subtypes of childhood maltreatment and different suicide behaviour involvement. Methods A multistage cluster sampling method was adopted from April to December 2021 for adolescents aged 12 to 18 across five representative provinces of China. The Childhood Trauma Questionnaire-Short Form was used to measure childhood maltreatment subtypes. Suicide behaviour involvement was classified as none group, suicide ideator, suicide planner and suicide attempter. Confounding variables include demographic characteristics, smoking, drinking alcohol, depression and anxiety. Results Among a total of 18,980 adolescents, 2021 (10.6%) were suicide ideator, 1595 (8.4%) were suicide planner and 1014 (5.3%) were suicide attempter. Rural females had the highest proportion of suicide ideator (13.8%) and suicide planner (11.5%). Multinomial logistic regression analysis indicated that five childhood maltreatment subtypes were independently associated with suicide behaviours, except for associations between sexual abuse and suicide ideator as well as suicide planner (p > 0.05). Moreover, these associations differ by sex and residence. After adjusted for interactions of different subtypes, structural equation model indicated that the direct effects of childhood maltreatment subtypes on suicide behaviours from high to low were emotional abuse (β = 0.363, p < 0.001), physical abuse (β = 0.100, p < 0.001) and sexual abuse (β = 0.033, p = 0.003), while the effects of physical neglect and emotional neglect were not significant (p > 0.05). Conclusions Five subtypes of childhood maltreatment have specific and non-equivalence associations with suicide behaviours. Emotional abuse may have the strongest effect, and sexual abuse have an acute effect on suicide behaviours. Suicide prevention programs for Chinese adolescents could focus on those who experienced emotional, physical and sexual abuse. Furthermore, strategies should be tailored by sex and residence, and rural females deserve more attention.

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The Association Between Suicide Attempts, Anxiety, and Childhood Maltreatment Among Adolescents and Young Adults With First Depressive Episodes

Cited by 9 publications

References 62 publications

Suicide attempt rate and the risk factors in young, first-episode and drug-naïve Chinese Han patients with major depressive disorder

Suicide attempt rate and the risk factors in young, first-episode and drug-naïve Chinese Han patients with major depressive disorder

Suicides among Children and Adolescents in Paraguay: An 18-year National Exploratory Study (2004–2022)

Specific effects of five subtypes of childhood maltreatment on suicide behaviours in Chinese adolescents: the moderating effect of sex and residence

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