The Association Between Sedentary Behavior and Sarcopenia Among Adults Aged ≥65 Years in Low- and Middle-Income Countries

Smıth, Lee; Tully, Mark A.; Jacob, Louis; Blackburn, Nicole E.; Adlakha, Deepti; Caserotti, Paolo; Soysal, Pınar; Veronese, Nicola; Sánchez, Guillermo Felipe López; Vancampfort, Davy; Koyanagi, Ai

doi:10.3390/ijerph17051708

Cited by 56 publications

(50 citation statements)

References 31 publications

(43 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another limitation is noted by the heterogeneity of the studied sample, which makes it difficult to associate the results with age, sex and functional level. However, the sample heterogeneity allowed the recruitment of sarcopenic seniors, who are generally older, have less body mass, body mass index [61] and are more sedentary [62]. Despite the low number of sarcopenic older adults studied (six women and five men), the frequency of the disease obtained (11.7%) was similar to the global prevalence reported in the literature (10%) [4].…”

Section: Discussionsupporting

confidence: 61%

One-repetition submaximal protocol to measure knee extensor muscle strength among older adults with and without sarcopenia: a validation study

Abdalla

Carvalho

Santos

et al. 2020

BMC Sports Sci Med Rehabil

View full text Add to dashboard Cite

Background: Dynamic knee extensor muscle strength is a valid measure among healthy older adults but has not been tested in the sarcopenia condition. This study's objective was to test the validity of a one-repetition submaximal strength protocol to measure dynamic knee extension strength in older adults with and without sarcopenia. Methods: Ninety-four physically independent older adults (female: n = 64, 60 to 85 years; male: n = 29, 60 to 85 years) participated in this study in Brazil during 2016-2017. Sarcopenia was classified and isokinetic unilateral knee extension strength was measured at 60°/s. Bilateral dynamic knee extension strength was estimated with an extensor chair using one-repetition submaximal protocol. Validity was determined using Spearman's correlation with isokinetic muscle strength. Results: The frequency of sarcopenia was 11.7%. Sarcopenic individuals presented lower body mass, body mass index and skeletal muscle index. Only chronological age was higher among the sarcopenic individuals. A high correlation was found between isokinetic unilateral knee extension strength and bilateral estimated one-repetition with submaximal protocol (r = 0.74; p < 0.001), when the presence (r = 0.71; p = 0.014) and absence of sarcopenia (r = 0.74; p < 0.001) were considered. The validity of the one-repetition submaximal protocol for bilateral knee extension was confirmed. Conclusions: The estimated measure of bilateral knee extension muscle strength can be used to monitor adaptations promoted by physical exercise for older adults with and without sarcopenia. The validation enable studies that will propose cutoff points to identify sarcopenia with this submaximal protocol. This will enable early diagnosis and better management of sarcopenia, a disease with adverse impacts for older adults.

show abstract

Section: Discussionsupporting

confidence: 61%

One-repetition submaximal protocol to measure knee extensor muscle strength among older adults with and without sarcopenia: a validation study

Abdalla

Carvalho

Santos

et al. 2020

BMC Sports Sci Med Rehabil

View full text Add to dashboard Cite

show abstract

“…These findings suggest that accumulating SB in long uninterrupted bouts, in addition to total SB volume, had an important association with physical function. Potential mechanisms for the negative impact of high levels of SB on physical function are complex but some suggestions have included SB displacing time away from MVPA, increased levels of adiposity and reduced levels of anti‐inflammatory markers in combination which could lead to increased muscle atrophy and may lead to increased risk of sarcopenia in older adults 32 …”

Section: Discussionmentioning

confidence: 99%

Associations of sedentary behavior bouts with community‐dwelling older adults' physical function

Wilson

McMullan

Blackburn

et al. 2020

Scandinavian Med Sci Sports

Self Cite

View full text Add to dashboard Cite

The study aim was to explore associations between sedentary behavior (SB) bouts and physical function in 1360 community‐dwelling older adults (≥65 years old). SB was measured using an ActiGraph wGT3X + accelerometer for seven consecutive days at the dominant hip and processed accordingly. Various SB bout lengths were assessed including: 1‐ to 9‐minutes; 10‐ to 29‐minutes; 30‐ to 59‐minutes; and ≥60‐minutes, as well as maximum time spent in a SB bout. Total SB time was adjusted for within the SB bout variables used (percentage SB time in the SB bout length and number of SB bouts per total SB hour). Physical function was assessed using the 2‐minute walk test (2MWT), 5‐times sit‐to‐stand (chair stand) test, and unipedal stance test (UST). Hierarchical linear regression models were utilized. Covariates such as moderate‐vigorous physical activity (MVPA), demographic and health characteristics were controlled for. Lower percentage time spent in ≥60‐minute SB bouts was significantly (P < .05) associated with longer 2MWT distance while lower numbers of ≥60‐minute SB bouts were associated with longer 2MWT distance, shorter chair stand time and longer UST time. There were mixed associations with physical function for 10‐ to 29‐minute SB bouts. In a large cohort of European older adults, prolonged SB bouts lasting ≥60‐minutes appear to be associated with reduced physical function after controlling for MVPA and numerous other important covariates. Besides reducing SB levels, these findings suggest there is a need to regularly interrupt prolonged SB to improve physical function in older adults.

show abstract

“…Several studies have provided robust evidence on the relationship between sedentary behavior, physical activity and sarcopenia. 11,[13][14][15][16][17][18] However, the association between sedentary behavior, physical activity and frailty has been less investigated. A recent systematic review investigated the association of sedentary behavior and frailty and highlighted the heterogeneity of samples included across studies, which may limit the generalizability of the results.…”

Section: And the World Healthmentioning

confidence: 99%

Association between frailty syndrome and sedentary behavior among community-dwelling older adults in the Amazon region: a cross-sectional study

et al. 2021

View full text Add to dashboard Cite

BACKGROUND: Existence of an association between sedentary behavior and frailty among older adults has been suggested. However, there is a lack of studies conducted in Brazil, especially in areas of the Amazon region. OBJECTIVE: To analyze the association between frailty syndrome and sedentary behavior among communitydwelling older adults. DESIGN AND SETTING: Cross-sectional study carried out in Macapá, state of Amapá, Brazil. METHODS: Frailty status was assessed using Fried's frailty phenotype, and sedentary behavior was evaluated using two questions concerning time spent in a seated position, from the International Physical Activity Questionnaire (IPAQ). A multinomial logistic regression model was used to verify the association between frailty syndrome and sedentary behavior. RESULTS: The final study sample was made up of 411 older adults with a mean age of 70.14 ± 7.25 years and an average daily duration of sedentary behavior of 2.86 ± 2.53 hours. The prevalence of non-frailty was 28.7%, prevalence of pre-frailty was 58.4% and prevalence of frailty was 12.9%. The adjusted analysis showed that there were independent associations between sedentary behavior and pre-frailty (odds ratio, OR = 1.18; 95% confidence interval, CI: 1.03-1.34) and between sedentary behavior and frailty (OR = 1.20; 95% CI: 1.02-1.40). CONCLUSION: Frailty and pre-frailty status were associated with sedentary behavior among community-dwelling older adults.

show abstract

The Association Between Sedentary Behavior and Sarcopenia Among Adults Aged ≥65 Years in Low- and Middle-Income Countries

Cited by 56 publications

References 31 publications

One-repetition submaximal protocol to measure knee extensor muscle strength among older adults with and without sarcopenia: a validation study

One-repetition submaximal protocol to measure knee extensor muscle strength among older adults with and without sarcopenia: a validation study

Associations of sedentary behavior bouts with community‐dwelling older adults' physical function

Association between frailty syndrome and sedentary behavior among community-dwelling older adults in the Amazon region: a cross-sectional study

Contact Info

Product

Resources

About