The Association between Male Asthma and Lower Urinary Tract Symptoms Evaluated by the International Prostate Symptom Score: A Population-Based Study

Abstract

Objectives: We explored the association between asthma severity and lower urinary tract symptoms (LUTS) using the International Prostate Symptom Score in a population-based study of males (aged ≥19 years) and evaluated voiding and urine storage symptoms. Methods: This was a cross-sectional study of 101,848 males, 2,544 of whom had asthma, who participated in the 2011 Korean Community Health Survey. All subjects were assessed in terms of sociodemographic data, pre-existing conditions, and the presence of LUTS. Logistic regression was used to identify risk factors for LUTS in asthmatics. Results: Urine storage symptoms (frequency, urgency, and nocturia) and voiding symptoms (straining, a weak stream, intermittency, and incomplete emptying) were significantly higher in the asthma group than in the non­asthma group (all p < 0.001). Moderate and severe LUTS were significantly more common in the asthma group (moderate, 24.3%; severe, 22.5%) than in the nonasthma group (moderate, 9.5%; severe, 2.9%). Compared to the mild LUTS group, the odds ratio (OR) for asthma was 2.21 (95% confidence interval [CI] 1.99–2.46) in the moderate LUTS group, and 3.04 (95% CI 2.64–3.51) in the severe LUTS group. In a model evaluating multiple variables, the OR for asthma in the moderate LUTS group was 1.95 (95% CI 1.74–2.16) and that in the severe LUTS group was 2.17 (95% CI 1.87–2.53). Asthma was associated with both voiding and storage symptoms. Conclusions: Male asthma was associated with moderate-to-severe LUTS. More aggressive urological diagnosis and treatment are needed for patients with asthma.

Clinical Correlation Between Overactive Bladder and Allergy in Children

“…Soyer et al (10) revealed that the incidence of urgent and frequent urination was higher in asthmatic children. A cross-sectional cohort study involving 101,848 adult males from South Korea demonstrated that asthma was associated with moderate and severe lower urinary tract symptoms (11).…”

Clinical Observation of the Correlation Between Overactive Bladder and Atopic Constitution in Children

“…A study of 178 children with asthma by Soyer et al found that asthmatic children younger than 6 years of age were at increased risk for frequent urination and urinary urgency, which occurred in 47.1% of the asthmatic children studied (5). A recent study of the relationship between asthma severity and lower urinary tract symptoms in adult men concluded that the asthmatic group had significantly higher urinary storage symptoms (frequent urination, urgency, and nocturia) and urination symptoms (tension, weakness, intermittent, and incomplete emptying) than the non-asthmatic group (6).…”