2017
DOI: 10.1016/j.jtumed.2016.07.010
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The association between interleukin 6 −174 G/C gene polymorphism and the risk of osteoporosis: A meta-analysis

Abstract: Objectives This study aimed to investigate the association between the IL6 −174 G/C gene polymorphism and the risk of osteoporosis by performing a meta-analysis. Methods Published literature from PubMed and Embase databases was searched for eligible publications. The following information was extracted from each study: Name of first author, year of publication, country of origin, sample size of cases and controls, and size of each allele. The combined odds ratio (ORs) a… Show more

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Cited by 17 publications
(14 citation statements)
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“…In effort to reach this goal, we collected several studies from PubMed and Embase concerning this association to calculate a poolled odd ratio (OR) and 95% confidence interval (CI) using fixed or random effect model. This design of the study was adapted from our previous meta-analysis 51, 52, 53, 54, 55…”
Section: Methodsmentioning
confidence: 99%
“…In effort to reach this goal, we collected several studies from PubMed and Embase concerning this association to calculate a poolled odd ratio (OR) and 95% confidence interval (CI) using fixed or random effect model. This design of the study was adapted from our previous meta-analysis 51, 52, 53, 54, 55…”
Section: Methodsmentioning
confidence: 99%
“…To reach this goal, several studies regarding the association between hip geometry and femoral neck fractures were collected for calculating combined odds ratios and 95% confidence intervals (ORs 95% CI) and assessed using fixed or random effect model. The design was adapted from our previous studies [20] , [21] , [22] , [23] , [24] . Articles were searched in PubMed and Embase.…”
Section: Methodsmentioning
confidence: 99%
“…To reach this purpose, published papers from PubMed, Embase, Cohcrane, and Web of science were collected for calculation of odd ratio (OR) and 95% confidence interval (95%CI) using either random or fixed effect model. The protocols in our current study including papers selection, data extraction, quality assessment, and statistical analysis were adapted from our previous meta-analyses [19][20][21][22], and we also used the checklist of the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) to guide the protocols in our study [23].…”
Section: Methodsmentioning
confidence: 99%