The Association Between Ferritin and Vitamin D Levels in Premenopausal Fibroid Uterus Cases With Anemia

Abstract

The present study aimed to evaluate the association between serum ferritin and vitamin D levels in fibroid uterus cases presenting with anemia. Methods Sixty premenopausal women with uterine fibroids (30 associated with anemia and 30 without anemia) were enrolled as cases and control. All participants were evaluated on the basis of a questionnaire, which included queries related to obstetric, medical, and sociodemographic history. Peripheral blood smear, complete blood count (CBC), hemoglobin (Hb), and serum ferritin concentration were measured by a fully automated analyzer, and 25(OH) vitamin D level was measured by enzyme-linked immunosorbent assay (ELISA). Results There was a significant difference in ferritin levels between cases and control (p<0.001). The exposure to sunlight was moderate (one-hour exposure) in all subjects, eliminating the confounding effect of sunlight exposure influencing vitamin D levels. The median vitamin D level in cases was 5.0 ng/ml [interquartile range (IQR): 4.8], and that in control was 18.4 ng/ml (IQR: 7.9; p<0.001). A strong positive correlation of (r)=0.616 (p<0.001) was found between serum ferritin and vitamin D levels. Conclusion Fibroid uterus cases with anemia are more prone to vitamin D deficiency as compared to cases without anemia. Vitamin D estimation in fibroid uterus cases presenting with anemia would be useful for better patient management.

Quantitative Analysis of the Steroidal Calcitriol-Mediated Regulation of the Serological Components Responsible for IDA and TSH Disorders in Reproductive and Nonproductive Women

“…The ferritin level in the human body indicates the iron status and iron storage. Ferritin levels are lower in people who have iron deficiency anemia, but they may be higher in people with inflammation and chronic disease-related Anemia [60]. However, in the present analysis, the range of the ferritin level was from 21 ng/mL to 166 ng/mL with some fluctuations, and calcitriol level was between the ranges of 8 to 26.29 ng/mL respected to the normal control.…”

Factors Associated with Hypovitaminosis D in People Living with HIV/AIDS (PLWHA) Followed up in Porto-Novo in 2019

“…In addition, subjects with anemia were at increased risk of vitamin D deficiency according to Kumari et al [23] and Mehta S et al [24]. A low-protein diet associated with vitamin D deficiency was noted by Parva et al [25].…”

Evaluation of Osteogenic Potential of a Polysaccharide-Based Hydrogel Coating on Titanium

“…Dental implants are an established treatment modality for the functional and esthetic rehabilitation of missing teeth [ 1 , 2 ]. Materials for dental implants need to be stable, chemically inert, corrosion resistant, biocompatible, and should have osteogenic potential [ 2 ].…”

“…Dental implants are an established treatment modality for the functional and esthetic rehabilitation of missing teeth [ 1 , 2 ]. Materials for dental implants need to be stable, chemically inert, corrosion resistant, biocompatible, and should have osteogenic potential [ 2 ]. The most popular material for implants in dentistry is still commercially pure titanium (grades 1-4), primarily due to its exceptional mechanical strength, corrosion resistance, and biocompatibility [ 2 - 4 ].…”

“…Materials for dental implants need to be stable, chemically inert, corrosion resistant, biocompatible, and should have osteogenic potential [ 2 ]. The most popular material for implants in dentistry is still commercially pure titanium (grades 1-4), primarily due to its exceptional mechanical strength, corrosion resistance, and biocompatibility [ 2 - 4 ]. Titanium forms a stable titanium oxide (TiO2) layer on the surface that is biocompatible and provides high corrosion resistance [ 5 ].…”