The Association between Ambient Temperature and Childhood Hand, Foot and Mouth Disease in Chengdu, China: A Distributed Lag Non-linear Analysis

Yin, Fei; Zhang, Tao; Liu, Lei; Lv, Qiang; Li, Xiaosong

doi:10.1038/srep27305

Cited by 35 publications

(43 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More researchers explored the associations between meteorological factors and hand, foot, and mouth disease. [27][28][29] But no studies on the associations between meteorological factors and SFTS were conducted using DLNM to date.…”

Section: Discussionmentioning

confidence: 99%

Association between Severe Fever with Thrombocytopenia Syndrome Incidence and Ambient Temperature

Sun

Lu²,

Yang³

et al. 2018

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Severe fever with thrombocytopenia syndrome (SFTS) is emerging in China. To explore the lagged effects and nonlinear association between temperature and SFTS, we collected data on ambient temperature and SFTS cases and analyzed the data using a distributed lag nonlinear model. A total of 1,933 SFTS cases were reported in the study area from 2011 to 2015. Our study revealed a nonlinear relationship between weekly temperature and SFTS. The exposure-response curve was an approximately reversed U-shaped peak at 23°C. High temperatures had acute and short-term effects, whereas low temperatures had persistent and long-term effects. The effects of lower temperatures (1.62°C and 6.97°C) could last 24 weeks, but the effect of 29.30°C was not significant at lag 8 weeks. Our results provide information to better understand the effect of temperature variation on SFTS and may have policy implications for disease prevention and control.

show abstract

Section: Discussionmentioning

confidence: 99%

Association between Severe Fever with Thrombocytopenia Syndrome Incidence and Ambient Temperature

Sun

Lu²,

Yang³

et al. 2018

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…Although most studies confirmed the association of high temperature and relative humidity with a high HFMD risk, some studies reported apparent differences in the elastic coefficients of these variables in difference locations [10,13,15,[20][21][22][23]. A study in the city of Guangzhou in south China city reported that a rise of 1°C in air temperature corresponded to an almost 10% increase (about 9·5%) in the risk of HFMD [15].…”

Section: Discussionmentioning

confidence: 99%

“…Although the previous studies detected a link between the risk of HFMD and meteorological factors, the association between these factors differed, depending on the region. For example, although most studies concluded that high temperatures and relative humidity were associated with a high risk of HFMD [15][16][17], some studies reported apparent differences in the exposure-response relationship in different locations and inverse influences of these factors [10,13,15,[20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Spatiotemporal risk mapping of hand, foot and mouth disease and its association with meteorological variables in children under 5 years

Xiao

2017

Epidemiol. Infect.

View full text Add to dashboard Cite

Hand, foot and mouth disease (HFMD) risk has become an increasing concern in the Beijing-Tianjin-Hebei region, which is the biggest urban agglomeration in north-eastern Asia. In the study, spatiotemporal epidemiological features of HFMD were analysed, and a Bayesian space-time hierarchy model was used to detect local spatial relative risk (RR) and to assess the effect of meteorological factors. From 2009 to 2013, there was an obvious seasonal pattern of HFMD risk. The highest risk period was in the summer, with an average monthly incidence of 4·17/103, whereas the index in wintertime was 0·16/103. Meteorological variables influenced temporal changes in HFMD. A 1 °C rise in air temperature was associated with an 11·5% increase in HFMD (corresponding RR 1·122). A 1% rise in relative humidity was related to a 9·51% increase in the number of HFMD cases (corresponding RR 1·100). A 1 hPa increment in air pressure was related to a 0·11% decrease in HFMD (corresponding RR 0·999). A 1 h increase in sunshine was associated with a 0·28% rise in HFMD cases (corresponding RR 1·003). A 1 m/s rise in wind speed was related to a 6·2% increase in HFMD (corresponding RR 1·064). High-risk areas were mainly large cities, such as Beijing, Tianjin, Shijiazhuang and their neighbouring areas. These findings can contribute to risk control and implementation of disease-prevention policies.

show abstract

“…The relationship between meteorological factors and HFMD outbreaks is often nonlinear in nature. In 23 of the 61 studies reporting a positive association with temperature, cases occurred most frequently within a specific temperature range, and extreme heat was associated with fewer case outbreaks . Whether or not this relates to viral biology or changes in human behavior at the extremes of temperature is unclear.…”

Section: Discussionmentioning

confidence: 99%

Temperature and humidity affect the incidence of hand, foot, and mouth disease: a systematic review of the literature – a report from the International Society of Dermatology Climate Change Committee

2018

View full text Add to dashboard Cite

Hand, foot, and mouth disease (HFMD) is an enterovirus-mediated condition that predominantly affects children under 5 years of age. The tendency for outbreaks to peak in warmer summer months suggests a relationship between HFMD and weather patterns. We reviewed the English-language literature for articles describing a relationship between meteorological variables and HFMD. Seventy-two studies meeting criteria were identified. A positive, statistically significant relationship was identified between HFMD cases and both temperature (61 of 67 studies, or 91.0%, reported a positive relationship) [CI 81.8-95.8%, P = 0.0001] and relative humidity (41 of 54 studies, or 75.9%) [CI 63.1-85.4%, P = 0.0001]. No significant relationship was identified between HFMD and precipitation, wind speed, and/or sunshine. Most countries reported a single peak of disease each year (most commonly early Summer), but subtropical and tropical climate zones were significantly more likely to experience a bimodal distribution of cases throughout the year (two peaks a year; most commonly late spring/early summer, with a smaller peak in autumn). The rising global incidence of HFMD, particularly in Pacific Asia, may be related to climate change. Weather forecasting might be used effectively in the future to indicate the risk of HFMD outbreaks and the need for targeted public health interventions.

show abstract

The Association between Ambient Temperature and Childhood Hand, Foot and Mouth Disease in Chengdu, China: A Distributed Lag Non-linear Analysis

Cited by 35 publications

References 24 publications

Association between Severe Fever with Thrombocytopenia Syndrome Incidence and Ambient Temperature

Association between Severe Fever with Thrombocytopenia Syndrome Incidence and Ambient Temperature

Spatiotemporal risk mapping of hand, foot and mouth disease and its association with meteorological variables in children under 5 years

Temperature and humidity affect the incidence of hand, foot, and mouth disease: a systematic review of the literature – a report from the International Society of Dermatology Climate Change Committee

Contact Info

Product

Resources

About