The Assessment of Residual Kidney Function After Living Donor Nephrectomy

Bieniasz, M.; Domagała, Piotr; Kwiatkowski, A.; Gozdowska, Jolanta; Krzysztof, O.; Kieszek, R.; Trzebicki, Janusz; Durlik, M.; Rowińskí, W; Chmura, A.

doi:10.1016/j.transproceed.2008.08.160

Cited by 18 publications

(10 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most donations (43 patients, 59.7 %) were carried out between genetically related people: parents (30), siblings (12), and cousins (1). Twenty-nine donors were genetically unrelated: spouse or partner (24), sister-in-law (1), and a friend (4).…”

Section: Resultsmentioning

confidence: 99%

“…Although it is evident that there are some changes similar to mild chronic kidney disease after kidney donation [10][11][12], the risk of the procedure is considered low for donors [7][8][9]. Nevertheless, newer studies indicate that LKD might be at risk of metabolic disorders and renal failure, which could lead to an increase in mortality [44].…”

Section: Discussionmentioning

confidence: 99%

“…LKDT is considered a safe procedure for donors, and there seems to be no increased risk of deteriorated renal function or other relevant disabilities like hypertension or proteinuria [7][8][9]. Nevertheless, mild changes after kidney donation similar to chronic kidney disease have been reported [10][11][12]. There appears to be some risk of the development of end-stage renal disease (ESRD) in the long term [13].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Long-term health-related quality of life of living kidney donors: a single-center experience

Benzing

Hau

Kurtz³

et al. 2015

Qual Life Res

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Long-term health-related quality of life of living kidney donors: a single-center experience

Benzing

Hau

Kurtz³

et al. 2015

Qual Life Res

View full text Add to dashboard Cite

show abstract

“…33 The adaptive hyperfunction of the residual kidney after a unilateral nephrectomy has a very rapid onset; effective renal plasma flow has been shown to increase by about 30% as early as 1 week after surgery and remains elevated for an extended period of time (>10 years). 22 It was also found that, after surgery, the large remaining renal mass had a greater ability to compensate for the loss.…”

Section: What Is Known About Renal Function After Nephrectomy In Humans?mentioning

confidence: 99%

Residual renal function after partial or radical nephrectomy for renal cell carcinoma

Chapman

Moore

Klarenbach

et al. 2013

CUAJ

View full text Add to dashboard Cite

Renal cell carcinoma (RCC) is often detected incidentally and early. Currently, open partial nephrectomy and laparoscopic total nephrectomy form competing technologies. The former is invasive, but nephron-sparing; the other is considered less invasive but with more loss of renal mass. Traditionally, emphasis has been placed on oncologic outcomes. However, a patient with an excellent oncologic outcome may suffer from morbidity and mortality related to renal failure. Animal models with hypertension and diabetic renal disease indicate accelerated progression of pre-existing disease after nephrectomy. Patients with RCC are older and they have a high prevalence of diabetes and hypertension. The progression of renal failure may also be accelerated after a nephrectomy. Our analysis of the available literature indicates that renal outcomes in RCC patients after surgery are relatively poorly defined. A strategy to systematically evaluate the renal function of patients with RCC, with joint discussion between the nephrologist and the oncologic team, is strongly advocated.Can Urol Assoc J 2010;4(5):337-343 Résumé L'hypernéphrome est souvent décelé fortuitement et au stade pré-coce. Actuellement, la néphrectomie partielle par voie ouverte et la néphrectomie totale par laparoscopie sont des technologies concurrentes. Tandis que la première est plus invasive, mais permet l'épargne des néphrons, la seconde est moins invasive mais entraîne une perte plus importante de masse rénale. Par le passé, on a mis l'emphase sur les résultats d'un point de vue oncologique. Cependant, un patient pour qui la chirurgie donne d'excellents résul-tats en matière d'élimination de la tumeur pourrait présenter une morbidité et une mortalité en lien avec une insuffisance rénale. Des modèles animaux de néphropathie avec hypertension et diabète indiquent une évolution accélérée des maladies préexistantes après la néphrectomie. Les patients présentant un hypernéphrome sont plus âgés; la prévalence du diabète et de l'hypertension est élevée. L'évolution de l'insuffisance rénale peut aussi être accélérée après la néphrectomie. Notre analyse des articles publiés montre que les résultats sur le plan de la fonction rénale après une chirurgie pour traiter un hypernéphrome sont relativement mal définis. Une straté-gie fondée sur une évaluation systématique de la fonction rénale des patients atteints d'hypernéphrome, avec discussion entre le néphro-logue et l'équipe de soins oncologiques, est fortement encouragée.

show abstract

“…[8][9][10] Our results regarding immediate postoperative complications are on par with those reported previously in different studies from across the world. [12][13][14][15][16][17][18][19] In particular, there were no perioperative deaths, and intermediate-term complications were also low. These results are reassuring and have contributed to the ongoing donations involving living donors at our center.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Hamid

Khan²,

Aziz³

et al. 2018

Exp Clin Transplant

View full text Add to dashboard Cite

Key words: Complications, Hypertension, Perioperative IntroductionKidney transplant is the treatment of choice for patients with end-stage renal disease (ESRD). Compared with long-term dialysis, kidney transplant procedures are cost-effective, offer improved quality of life, and confer a progressive survival benefit. 1,2 While the ESRD population continues to grow, the supply of kidneys for transplant from deceased donors is unlikely to increase significantly, resulting in a large gap between the demand for donor kidneys and supply. 3,4 Fortunately, living kidney donation has become an attractive alternative to transplants with deceased donations. With the advent of laparoscopic donor nephrectomy and constantly improving recipient outcomes, the number of living kidney donations has grown by 115% over the past decade. 5 From a recipient standpoint, living-donor transplant is regarded as superior to deceased-donor transplant in every respect. Living-donor transplant allows for a full donor evaluation before transplant, elective scheduling of surgery at the time of optimized recipient health, and a minimum graft ischemic time during the transplant operation. 6 The major downside of living-donor renal transplant is that it subjects a healthy person to unnecessary surgery, with its attendant risks and a life after surgery with reduced renal mass. Fortunately, donor nephrectomy is a relatively safe procedure. The risk of donor death is most commonly cited as 0.03%, the risk of major complications is from 0.23% to 2.1%, and the risk of minor complications is from 8.0% to 14.7%. 7,8 The aim of the present study was to evaluate the short-and long-term outcomes of living-related kidney donors in terms of biochemical parameters and postnephrectomy complications at a single center in Pakistan.

show abstract

The Assessment of Residual Kidney Function After Living Donor Nephrectomy

Cited by 18 publications

References 12 publications

Long-term health-related quality of life of living kidney donors: a single-center experience

Long-term health-related quality of life of living kidney donors: a single-center experience

Residual renal function after partial or radical nephrectomy for renal cell carcinoma

Untitled

Contact Info

Product

Resources

About