In this review, the current evidence for objective outcome measures for working-age amputees and the usefulness of these measures in fitness for duty evaluations was examined. Although certain federal agencies have developed a process to evaluate amputees in specific job-task environments, this mechanism does not translate to more complex or physically demanding job environments, such as military, law enforcement, and firefighting. The medical standards for individuals with an amputation in federally regulated occupations as examples of current fitness standards for amputees, legal precepts, and current research on prosthetic outcomes were reviewed in an effort to identify criteria that could aid the examining physician in certifying an amputee as fit for duty for complex and/or physically demanding job environments. The need to develop criteria for a "well-managed amputee" is introduced.Preplacement examinations and fitness for duty evaluations are used in many workplaces, and serve to protect both the employee and the employer. For simplicity, we will use the