The application of hydrogels based on N-isopropylacrylamide and anionic comonomers

Abstract

Hydrogels represent three-dimensional networks of polymer chains that have the ability of absorption of a significant amount of water or biological fluid. A special group of hydrogels are copolymers which respond to changes of pH values and temperature. Desirable characteristics of temperature-and pH-sensitive hydrogels based on N-isopropylacrylamide and anionic comonomers for different applications, from pharmaceutical to the environmental one, can be designed by composition of copolymers. The presence of the amide and carboxyl group in the structure of these hydrogels enables their application as adsorbents in the processes of removing the pollutants from aqueous solutions. Hydrogels based on N-isopropylacrylamide and anionic comonomers represent desirable three-dimensional matrices for controlled and sustained release of agrochemicals and drugs in relation to temperature and pH of the surrounding medium. Hydrogels, as separation devices, perform the concentrating of compounds or microorganisms solutions by absorption of greater amounts of water. One more application of these copolymers is for immobilization of enzymes.

Remoción de plomo en solución acuosa usando criogeles basados en polyacrylamide como adsorbente: Estudio de equilibrio en modo batch

“…bioseparación (Carvalho et al, 2014), como la cromatografía de nano y micropartículas biológicas (Plieva et al, 2005), así como la separación, purificación, liberación de drogas, contaminantes ambientales biológicos, farmacéutica, médicas e ingeniería de tejidos (Sofia & Duarte, 2012;Zdravkovic, Nikolic, Ilic-Stojanovic, & Nikolic, 2017).…”

Hydrogels as Controlled Drug Delivery System: A Brief Review of Properties Classification and Synthesis

“…Neutral Hydrogels These hydrogels do not possess charged groups in their structure and swell by interaction of polymer network and water (Zdravković, Nikolić, Ilić-Stojanović, & Nikolić, 2017).…”