“…In a comparison of alleles calls from 2048 STR profiles between manual review with Genotyper and automated review with TrueAllele, only one significant difference was observed when the analyst using Genotyper interpreted a spike as a DNA peak at D8S1179, but TrueAllele correctly designated it as a spike (85). Validation studies with 290 676 STR markers found CompareCalls SM software, an automated allele concordance analysis system from Myriad Genetics, to be at least as accurate as 100% human technical review of STR profiles (86).…”