The applause sign in Parkinson’s disease patients is related to dysexecutive syndrome

Triple test, a diagnostic observation, can detect cognitive impairment in older adults

“…Finally, AS (i.e. a tendency to clap more than three times in response to the demonstration of clapping only three times) was present in various neurodegenerative diseases, such as PSP, Parkinson’s disease, corticobasal syndrome, multisystem atrophy, cortical dementias (e.g. AD and behavioural variant of frontotemporal dementia), and amyotrophic lateral sclerosis .…”

“…AD and behavioural variant of frontotemporal dementia), and amyotrophic lateral sclerosis . AS is considered a consequence of perseveration due to frontal lobe impairment, a part of dysexecutive syndrome . This sign is the one that would be least likely to be affected by cultural features.…”

“…Each of these signs has been previously evaluated in a limited number of studies, but the effectiveness of using these signs in combination in a large number of older adults with or without CI has not been evaluated . Moreover, these signs have not been studied in different locations and cultures.…”