The Antithrombic Activity of Carrageenin in Human Blood

Hawkins, W. W.; Leonard, Verna G.

doi:10.1139/o63-149

Cited by 18 publications

(4 citation statements)

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“…Many reports of anticoagulant activity and inhibited platelet aggregation of carrageenan exist (Hawkins et al 1962;Hawkins and Leonard 1963;Kindness et al 1979). Among the carrageenan types, λ-carrageenan (primarily from C. crispus) has approximately twice the activity of unfractionated carrageenan and four times the activity of κ-carrageenan (E. cottoni and Eucheuma spinosum).…”

Section: Carrageenansmentioning

confidence: 99%

Bioactive compounds in seaweed: functional food applications and legislation

Holdt

Kraan²

2011

J Appl Phycol

1,590

1,303

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Seaweed is more than the wrap that keeps rice together in sushi. Seaweed biomass is already used for a wide range of other products in food, including stabilising agents. Biorefineries with seaweed as feedstock are attracting worldwide interest and include low-volume, high valueadded products and vice versa. Scientific research on bioactive compounds in seaweed usually takes place on just a few species and compounds. This paper reviews worldwide research on bioactive compounds, mainly of nine genera or species of seaweed, which are also available in European temperate Atlantic waters, i.e. Laminaria sp., Fucus sp., Ascophyllum nodosum, Chondrus crispus, Porphyra sp., Ulva sp., Sargassum sp., Gracilaria sp. and Palmaria palmata. In addition, Undaria pinnatifida is included in this review as this is globally one of the most commonly produced, investigated and available species. Fewer examples of other species abundant worldwide have also been included. This review will supply fundamental information for biorefineries in Atlantic Europe using seaweed as feedstock. Preliminary selection of one or several candidate seaweed species will be possible based on the summary tables and previous research described in this review. This applies either to the choice of high valueadded bioactive products to be exploited in an available species or to the choice of seaweed species when a bioactive compound is desired. Data are presented in tables with species, effect and test organism (if present) with examples of uses to enhance comparisons. In addition, scientific experiments performed on seaweed used as animal feed are presented, and EU, US and Japanese legislation on functional foods is reviewed.

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Section: Carrageenansmentioning

confidence: 99%

Bioactive compounds in seaweed: functional food applications and legislation

Holdt

Kraan²

2011

J Appl Phycol

1,590

1,303

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“…Blood Coagulation. Carrageenan, in common with other sulfated polysaccharides, possesses anticoagulant activity (Hawkins and Leonard, 1963). Carrageenan, or degraded carrageenan, intravenously injected into rabbits has been shown to prolong the clotting time of blood (Anderson and Duncan, 1965).…”

Section: Experimental Procedures and Resultsmentioning

confidence: 99%

Nutritional quality of processed milk containing carrageenan

Tomarelli¹,

Tucker²,

Bauman³

et al. 1974

J. Agric. Food Chem.

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“…Among other properties, carrageenans present anticoagulant activity and inhibit platelet aggregation (Hawkins et al 1962, Hawkins andLeonard, 1963;Kindness et al , 1979). The principal basis of the anticoagulant activity of carrageenan is its anti-thrombotic property.…”

Section: Algal Carbohydrate Contentmentioning

confidence: 99%