The antioxidant activity of Zingiber officinale, Hibiscus sabdariffa, and Caesalpinia sappan combination

Abstract

Medicinal plants have been used in traditional treatment since a long time ago by local people in Indonesia. Nowadays, the trend in the consumption of medicinal plants, especially herbal drinks, is increasing. Zingiber officinale, Hibiscus sabdariffa, and Caesalpinia sappan are their main materials of medicinal plants. They were chosen because of their high antioxidant contents. Nevertheless, there is no scientific research on the antioxidant activity of the combination of the three extracts. Therefore, the purpose of this study was to determine the total flavonoid contents and antioxidant activity, as well as to compare the antioxidant enhancement pattern of the combination. Samples were extracted by successive maceration with hexane and ethyl acetate as solvents. Total flavonoids contents were determined through colorimetric analysis and antioxidant activity was determined based on the DPPH method with the IC50 value as a parameter. Total flavonoids of ethyl acetate extract from Z. officinale, H. sabdariffa, and C. sappan were 30.28±0.04; 24.81±0.03; and 24.01±0.04 mg QE/ gram extract, and the IC50 value were 51.36±0.05; 83.37±0.06; and 35±0.04 ppm. Total flavonoid contents of their

Phytochemical Profiling and Antioxidant Activities of Red Ginger (Zingiber officinale var. rubrum) Cultivated Eco-Farming

“…34 In contrast to research by Widyapuspa et al, who reported that red ginger ethyl acetate extract had an IC50 value of 51.36 ± 0.05. 51 Red ginger's antioxidant activity is linked to its total flavonoid and phenolic content. This activity is attributed to the ability of these compounds to donate electrons or hydrogen to free radicals.…”

POTENSI ANTIOKSIDAN INFUSA BUNGA TELANG (Clitoria ternatea), ROSELLA (Hibiscus sabdariffa) DAN DAUN STEVIA (Stevia rebaudiana) SEBAGAI ANTIDIABETES

“…Nilai aktivitas FRAP (%) sejalan dengan jumlah Fe 2+ yang terbentuk dari proses reduksi oleh infusa sampel uji. Dibandingkan pada penelitian terdahulu, ekstrak etil asetat Rosella memiliki aktivitas antioksidan menggunakan metode DPPH dengan nilai IC50 83,37 ppm (Widyapuspa et al, 2022), sedangkan berdasarkan penelitian dari (Widowati et al, 2022) bunga telang memiliki aktivitas FRAP dengan nilai IC50 5,56%. Daun Stevia memiliki inhibisi sebesar 62,681 % dengan metode DPPH (Garcia-Mier et al, 2021).…”

“…Senyawa fenolik dan flavonoid, memiliki aktivitas antioksidan melalui mekanisme donor hidrogen sebagai agen pereduksi, quenching oksigen singlet, berperan sebagai kelator radikal bebas (Skroza et al, 2022). Berdasarkan jumlah senyawa flavonoid total pada ekstrak etil asetat bunga Rosella sebesar 24,81 mg QE (Quersetin Equivalent) /gram ekstrak (Widyapuspa et al, 2022) lebih besar dibandingkan jumlah senyawa flavonoid total pada bunga telang yaitu 4,88 g QE (Quersetin Equivalent) /100% (Widowati et al, 2022). Hal ini sejalan dengan aktivitas FRAP bunga Rosella yang pada penelitian ini lebih besar dibandingkan bunga Telang.…”

Combination of polyherbal Phyllanthus reticulatus with Zingiber officinale and Cymbopogon citratus to optimize the antioxidant capacity

“…Many researchers studied about the combination polyherbal about ginger, lemongrass, and mangsian. The combination of ginger and sappan wood also increases antioxidant activity better than being separated reported (Widyapuspa et al, 2022). The analgesic and anti-inflammatory activity of a combination of Phyllanthus reticulatus and Mimosa pigra (Akhter et al, 2018).…”