The antimicrobial activity of gray-colored mineral trioxide aggregate (GMTA) and white-colored MTA (WMTA) under aerobic and anaerobic conditions

Ribeiro, Caroline Sousa; Scelza, Míriam Zaccaro; Júnior, Raphael Hirata; Oliveira, Lidia Maria Buarque de

doi:10.1016/j.tripleo.2010.02.008

Cited by 22 publications

(27 citation statements)

References 19 publications

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“…Ribeiro et al. (42) suggested that these variations might be the results of the methodology used, such as aerobic and anaerobic incubations. It has been shown that MTA in an aerobic atmosphere could generate reactive oxygen species (ROS), which have antimicrobial activity.…”

Section: Discussionmentioning

confidence: 99%

Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite

Odabaş¹,

Çınar²,

Akca

et al. 2011

Dental Traumatology

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The purpose of this in vitro study was to determine whether adding silver-zeolite (SZ) to mineral trioxide aggregate (MTA) would enhance the antimicrobial activity of MTA against Staphylococcus aureus (ATCC #25923), Enterococcus faecalis (ATCC #29212), Escherichia coli (ATCC#25922), Pseudomonas aeruginosa (ATCC #27853), Candida albicans (ATCC #90028), Porphyromonas gingivalis (ATCC #33277), Actinomyces israelii (ATCC #12102), and Prevotella intermedia (ATCC# 15032). SZ was added at 0.2% and 2% mass fraction concentration to MTA powder. The control group was MTA powder with no SZ. The antimicrobial effect test was accomplished by placing freshly mixed MTA specimens on agar plates inoculated with microorganisms and comparing the zones of inhibition at 24, 48, and 72 h. The amounts of silver ion release from MTA specimens were measured with atomic absorption spectrophotometry at 10-min, 24-, 48-, and 72-h periods. The pH of MTA specimens was measured with a pH meter at 10-min, 24-, 48-, and 72-h periods. MTA with 2% and 0.2% SZ specimens showed inhibitory effects on some microorganisms at all time periods, whereas no antimicrobial activity showed for P. intermedia and A. israelii. MTA without SZ inhibited C. albicans, E. Coli, and P. intermedia. The highest silver release was detected in 2% SZ MTA at 24 h. The incorporation of SZ may enhance the antimicrobial activity of MTA.

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Section: Discussionmentioning

confidence: 99%

Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite

Odabaş¹,

Çınar²,

Akca

et al. 2011

Dental Traumatology

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“…[27,28] Since MTA's generation of reactive oxygen species (ROS), responsible in part for its antimicrobial effect is decreased under anaerobic conditions, it has been proposed that MTA may not produce adequate ROS to inhibit certain bacterial strains. [29,30] We acknowledge that further evaluation of the antibacterial activity of NanoAg-MTA against additional common endodontic pathogens, such as Enterococcus faecalis, will strengthen our study findings, since E. faecalis is the most frequently recovered bacteria from failed endodontic treatment cases. [31] While DCT is suitable for materials less likely to disperse in aqueous media, [19] our novel MEIT assay has successfully measured the antibacterial activity of a water-based NanoAg-MTA root end material.…”

Section: Discussionmentioning

confidence: 52%

In vitro evaluation of the antimicrobial activity of nanosilver-mineral trioxide aggregate against frequent anaerobic oral pathogens by a membrane-enclosed immersion test

et al. 2015

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“…Both cements showed antimicrobial activity under aerobic conditions. On the other hand, both cements were not able to induce any bacterial inhibition under anaerobic conditions, suggesting that the inhibitory action is a result of ROS production [ 143 ].…”

Section: Antibacterial Propertiesmentioning

confidence: 88%

Properties of Hydrated Mineral Trioxide Aggregate

Tanomaru-Filho

Guerreiro-Tanomaru

2014

Mineral Trioxide Aggregate in Dentistry

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MTA has been currently commercialized in two different forms, the gray (GMTA) and the white version (WMTA). In particular, the white MTA was developed due to the potential discoloration promoted by the gray version of the cement. The chemical composition of the MTAs is very similar to that of Portland cement despite the addition of components containing bismuth in the MTA's cements [ 91 , 128 ], which aims to confer radiopacity to the materials [ 34 ]. The mixture of the MTA powder with distilled water results in the formation of by-products, such as calcium hydroxide and calcium silicate hydrate gel [ 27 , 28 ] as discussed in Chap. 2 . The particular mechanism of hydration and the structure of the set material result in particular properties displayed by the set MTA.The initial pH of the MTA is approximately 10.2, but it increases to 12.5 after 3 h immersed in solution [ 177 ]. MTA has the ability to sustain high values of pH during long periods [ 75 ]. The high pH values exhibited by MTA are attributed to the constant release of calcium and the formation of calcium hydroxide.Several studies had reported release of calcium from MTA [ 12 , 74 , 131 ]. The calcium ion release is enhanced when calcium chloride is added as an accelerator to MTA [ 12 ]. Moreover, when MTA was placed into the root canals of teeth with simulated radicular resorption, a greater calcium ion release was detected in comparison to teeth not fi lled with MTA [ 131 ]. Setting TimeThe hydration of the MTA powder produces a colloidal gel, which solidifi es and results in a solid structure. MTA is prepared by mixing the powder with distilled water using a ratio of 3:1 (powder/distilled water) [ 184 ].

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The antimicrobial activity of gray-colored mineral trioxide aggregate (GMTA) and white-colored MTA (WMTA) under aerobic and anaerobic conditions

Cited by 22 publications

References 19 publications

Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite

Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite

In vitro evaluation of the antimicrobial activity of nanosilver-mineral trioxide aggregate against frequent anaerobic oral pathogens by a membrane-enclosed immersion test

Properties of Hydrated Mineral Trioxide Aggregate

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