The Anatomy of the Female Gubernaculum Is Different From the Male*

Attah, A. A.; Hutson, John M.

doi:10.1111/j.1445-2197.1991.tb00239.x

Cited by 32 publications

(17 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It differentiates into the suspensory ligament of the ovary and the round ligament of the uterus, the distal end of which remains attached to the abdominal wall muscle and subcutaneous fascia a t the external ring in the human (Attah & Hutson, 1991). This study shows that the same is true for the adult female mouse.…”

Section: Discussionsupporting

confidence: 52%

“…A biphasic model for testicular descent was proposed in 1985 (Hutson, 1985) and is gaining increasing support (Fallat et al, 1992; Attah & Hutson, 1991;Wensing, 1988;Hutson, 1986). Transabdominal and inguino-scrota1 phases were proposed to be controlled by separate hormones and mechanisms because descent of the testis was arrested in the inguinal region in mice with complete androgen resistance (TFM) (Hutson, 1986;Hutson & Donahoe, 1986).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Gubernaculum in adult female, adult male and TFM male mice

Griffiths¹,

Momose²,

Hutson³

1993

Int J of Andrology

Self Cite

View full text Add to dashboard Cite

SummaryThere is still controversy over whether androgens are involved in gubernacular migration during descent of the testis, prompting a review of anatomical events controlled by androgens. The gubernacular position in adult female, male, and testicular feminized male (TFM) mice (with complete androgen resistance) was observed macroscopically to determine its caudal limit and whether the adult TFM male still contained guvernacular bulk. The length of the processus vaginalis was measured, and the presence of a differentiated cremaster muscle was determined histologically. In 10 adult female mice there was neither a processus vaginalis nor a cremaster muscle, and the gubernaculum (round ligament of the ovary) attached to the external inguinal ring. In 10 adult TFM mice the gubernaculum ended at or just beyond the external ring, and was present in an amount corresponding to its size at the end of the outgrowth phase of development, with secondary infiltration by fat. The processus vaginalis was poorly developed, the cremaster muscle was undifferentiated, and there was no eversion of the cremaster sac. In 10 normal adult male mice the gubernaculum and testis had migrated to the scrotum, and the gubernaculum had regressed fully. Because gubernacular development in the androgen-resistant mouse ceases after termination of transabdominal testicular migration, the anatomy of the adult confirms that, in the mouse, normal androgenic function is essential for eversion of the cremaster sac and gubernacular migration beyond the groin to the genital folds.

show abstract

Section: Discussionsupporting

confidence: 52%

Section: Introductionmentioning

confidence: 99%

The Gubernaculum in adult female, adult male and TFM male mice

Griffiths¹,

Momose²,

Hutson³

1993

Int J of Andrology

Self Cite

View full text Add to dashboard Cite

show abstract

“…No migration of the round ligament occurs leaving it ending just outside the external ring. 8 The processus vaginalis forms as a small evagination of the peritoneum on the gubernacular mesenchyme at the future superficial inguinal ring. 9 Hollinshead described the round ligament as a flattened band arising from the lateral border of the uterus, immediately below the attachment of the ovarian ligament.…”

Section: Discussionmentioning

confidence: 99%

“…10 Attah and Hutson observed the gubernaculum in the 30wk old male fetus and found that it ended outside the external ring, later migrating into the scrotum under androgenic control. 8 Anatomy of the round ligament was defined by dissection and photography on post mortem examination of 10 females (0-11yrs) dying of non genital disorders. The round ligament ended just outside the external ring in all females with neither attachment nor extension to the caudal labium.…”

Section: Discussionmentioning

confidence: 99%

Morphologic and histological differentiation of gubernaculum in female fetus: a cadaveric study

2017

View full text Add to dashboard Cite

Background: In both male and female fetuses inguinal canal development entails a complex sequence of anatomic events involving the gubernaculum and processus vaginalis. Much has been written about the embryological development of the genital system, particularly the male genital system and the descent of the testes from the abdominal cavity into the scrotum. In this process, the gubernaculum plays a relevant although still unclear role. Despite all the studies that have been performed, controversy still exists in this anatomical region.Methods: Twenty round ligaments of uterus were dissected from female fetuses and microscopic structure was studied under light microscope using haematoxylin and eosin stain. The specimens were collected from female fetuses (8wks-26wks). One male fetus was also dissected.Results: Gubernaculum plays a crucial role in the development of the inguinal region. The gubernaculum is directly associated with the migration of the testis through the inguinal canal and probably to the scrotum; but the inguinal canal is present before testicular descent and females have both an inguinal canal and gubernaculum, although the ovaries do not migrate through the abdominal wall.Conclusions: In this anatomical region, and despite all the studies that have been performed, controversy still exists. This article attempts to study the morphology and histology and the differentiation of the gubernaculum with age.

show abstract

“…Whatever the origin, distal attachment and composition of this structure remain controversial. The round ligament (RL) in females is usually accepted as the postnatal G [1,2,11]. RL is described to lie in the inguinal hernia sac [12], and to course distally within the inguinal canal [11], but the origin, distal attachment and composition of this structure also remain controversial.…”

Section: Introductionmentioning

confidence: 99%

A Reevaluation of the Structures Accepted to Represent the Postnatal Gubernaculum

Tanyel¹,

Talim

Kale

et al. 2002

Urol Int

View full text Add to dashboard Cite

Introduction: The structure called the residual gubernaculum (G) has been evaluated to define its origin. Materials and Methods: Girls operated for inguinal hernia (n = 7) and boys operated for undescended testis (n = 12), inguinal hernia (n = 7), hydrocele of the cord (n = 1), and ectopic (n = 1) and entrapped (n = 1) testes were evaluated. Attachments of the structures coursing distally from the sacs were identified, and they were removed en block. Three samples, first from the distal part of the sac with the beginning of the fibrous structure, second from the midportion, and third from the most distal part, were prepared and stained with hematoxylin-eosin, trichrome and elastic van Gieson. Histologic structures within the samples were determined and compared with Mann-Whitney U test. Results and Conclusions: Structures called the residual G differed from the walls of accompanying sacs by only the absence of mesothelial lining. Therefore, the structure called the residual G in boys with an undescended testis and the round ligament in girls actually represent the obliterated processus vaginalis.

show abstract

The Anatomy of the Female Gubernaculum Is Different From the Male*

Cited by 32 publications

References 2 publications

The Gubernaculum in adult female, adult male and TFM male mice

The Gubernaculum in adult female, adult male and TFM male mice

Morphologic and histological differentiation of gubernaculum in female fetus: a cadaveric study

A Reevaluation of the Structures Accepted to Represent the Postnatal Gubernaculum

Contact Info

Product

Resources

About