The amniotic fluid index in normal human pregnancy

Moore, Thomas R.; Cayle, Jonathan E.

doi:10.1016/0002-9378(90)90009-v

Cited by 528 publications

(342 citation statements)

References 12 publications

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“…1 The post-term pregnancy, which occurs among <5% of gravidas 2 has been associated with an increased perinatal mortality rate. [3][4][5] Perinatal morbidity has also been noted to be higher in post-term pregnancies including meconium-stained amniotic fluid and meconium aspiration syndrome, 6 oligohydramnios, 7 macrosomia, 8,9 fetal birth injury, 10 rates of fetal distress in labor, 11 and rates of cesarean delivery. 5,12 While it is well established that these risks are increased in post-term pregnancy, what has received less attention is whether and to what extent these risks increase before 42 weeks' gestation.…”

Section: Introductionmentioning

confidence: 99%

Maternal complications of pregnancy increase beyond 40 weeks of gestation in low-risk women

Caughey

Bishop

2006

J Perinatol

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Objective: We sought to determine when rates of maternal pregnancy complications increase for low-risk nulliparous and multiparous women at term. Methods:We designed a retrospective cohort study of low-risk women delivered beyond 37 weeks gestational age from 1976 to 2001. Rates of mode of delivery and maternal complications of labor and delivery were examined by gestational age with both bivariate and multivariate analyses. Statistical significance was designated by P<0.05.Results: We found that among the 32 828 low-risk women who delivered at 37 completed weeks and beyond, the rates of primary cesarean delivery, operative vaginal delivery, third-or fourth-degree perineal lacerations, and chorioamnionitis all increased at 40 weeks of gestation (P<0.001), and the rate of postpartum hemorrhage increased at 41 weeks of gestation (P<0.001). These increases of rates of complications were larger and increased at an earlier gestational age among nulliparous women. Conclusion:We found that the risk of maternal complications for otherwise low risk nulliparous and multiparous women increased as pregnancy progressed beyond 40 weeks of gestation. Counseling of women who progress past their EDC should include comparing the risks of induction of labor to that of expectant management.

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Section: Introductionmentioning

confidence: 99%

Maternal complications of pregnancy increase beyond 40 weeks of gestation in low-risk women

Caughey

Bishop

2006

J Perinatol

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“…AFV is characteristically assessed using the four-quadrant index or by measurement of a single maximum vertical pocket [1]. AFV is known to correlate with maternal hydration status [2] and clinical dehydration is known to be more common in June, July and August (in the Northern Hemisphere) [3].…”

Section: Introductionmentioning

confidence: 99%

Is there a seasonal variation in the diagnosis of oligohydramnios?

Varner

Noble

Dombrowski

et al. 2005

The Journal of Maternal-Fetal & Neonatal Medicine

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Objective. We hypothesized that oligohydramnios would be diagnosed more frequently in the warm summer months when dehydration might be more common. Methods. The clinical diagnosis of oligohydramnios was extracted from the databases of four completed National Institute of Child Health and Human Development Maternal Fetal Medicine Units Network protocols. These data were stratified by quarter of delivery and compared using Fisher's Exact Test. Results. The clinical diagnosis of oligohydramnios was made more frequently in deliveries occurring in the summer months of June, July and August as compared with the remainder of the calendar year (7.2% vs 5.9%, p = 0.0178). Conclusions. In these studies the diagnosis of oligohydramnios is made more frequently in those pregnancies delivered during the summer months. Although not proven by this association, maternal dehydration may contribute to this finding.

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“…This finding has been reported to correlate with the severity of CDH (15). Polyhydramnios was defined as an amniotic fluid index of >25 (29).…”

Section: Prognostic Factors In Clinical Cdhmentioning

confidence: 91%

Amniotic lamellar body count and congenital diaphragmatic hernia in humans and in a rat model

et al. 2012

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Background:We examined the extent of fetal lung hypoplasia and lung maturation using the amniotic lamellar body count (LBc) in congenital diaphragmatic hernia (cDh). Methods: We obtained 30 amniotic fluid samples from human cDh cases during cesarean section. We assessed LBc, magnetic resonance imaging (MRI), and ultrasound findings for predicting the prognosis of cDh. We collected newborn amniotic fluid and lung tissue at embryonic day (e)21 from normal and nitrofeninduced cDh rats (administered 100 mg orally at e9). amniotic LBcs in rats were measured using light microscopy. results: In human cDh, LBc was significantly higher in the surviving than in the deceased group (P < 0.01). a significant positive correlation was observed between LBc and percentage of fetal lung volume on MRI (P < 0.001; r = 0.716). In rats, LBc was significantly higher in controls than in cDh rats (P < 0.01) and correlated with fetal lung weight. conclusion: We conclude that LBc is useful for predicting lung hypoplasia in human cDh after 35 gestational weeks and in a rat model of nitrofen-induced cDh.

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The amniotic fluid index in normal human pregnancy

Cited by 528 publications

References 12 publications

Maternal complications of pregnancy increase beyond 40 weeks of gestation in low-risk women

Maternal complications of pregnancy increase beyond 40 weeks of gestation in low-risk women

Is there a seasonal variation in the diagnosis of oligohydramnios?

Amniotic lamellar body count and congenital diaphragmatic hernia in humans and in a rat model

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