The Amino Acid Composition of Some Purified Proteins

Internal redistribution of tissue protein synthesis in uremia

“…It could have been due, in part, to adrenal steroid hormone release (9) Changes in tissue free lysine levels (increased in uremic liver, decreased in uremic muscle) paralleled the changes in protein synthesis. Lysine is a major constituent of nuclear histones and cellular ribonucleoproteins (14), which are important regulators of tissue protein synthesis. Soon after partial hepatectomy, when the rate of hepatic protein synthesis accelerates, lysine content of liver tissue increases (15,16).…”

Chemical and Electron Microscope Studies on Fractions Prepared From Coats of Bacillus Spores

“…Perhaps the most outstanding finding was the very high content (12.0 %) of tyrosine. In distinction from the collagens where this tyrosine occurs in very low concentrations, the tyrosine content of the alkali-soluble proteins from the spore coats was higher than that of any of the 253 proteins whose analyses were compiled by Tristam & Smith (1963). Only papain has a tyrosine content approaching that of the protein from these spore coats.…”

“…The distinctiveness of the amino acid composition of the resistant residue was emphasized by the exceptionally high proportion of lysine; nearly one of every five of the identifiable amino acid residues was a lysine. The only protein reported to have a comparably high lysine content is cytochrome C (Tristam & Smith, 1963). If, alternatively, the high lysine is in the usual kind of side chain of polymucopeptide (Weidel & Pelzer, 1965), correspondingly high proportions of alanine, aspartic acid, glutamic acid and perhaps glycine would be expected.…”

Kidney and Breast Cysts: A Comparative Study of Fluids

“…A number of the amino acids that were found in the cyst fluids are present in blood and its components [16,17], When individual concentrations of these amino acids were rank ordered and profiles of their measured (in cyst fluids) versus reported (as available from the literature) concentrations were compared, some significant correla tions were found (table 3), specifically between the se quences of concentrations in blood and plasma versus those in all but the low-sodium breast fluids; between the sequences in hemoglobin and both high-and low-sodium kidney fluids, and between the sequence of amino acids in albumin and in low-sodium breast fluids.…”