1932
DOI: 10.1021/ja01346a037
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The Alkaloids of Argemone Mexicana

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Cited by 28 publications
(8 citation statements)
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“…1) is a natural plant alkaloid abundantly distributed in the plants like Sanguinaria canadensis and Chelidonium majus. [1][2][3][4][5] Sanguinarine has been the focus of extensive research for its potential drug value. In recent years considerable research on its antimicrobial, antifungal, antioxidant and anti-inammatory effects, [6][7][8][9][10] and ability for selective/ preferential elimination of cancer cells has been undertaken.…”
Section: Introductionmentioning
confidence: 99%
“…1) is a natural plant alkaloid abundantly distributed in the plants like Sanguinaria canadensis and Chelidonium majus. [1][2][3][4][5] Sanguinarine has been the focus of extensive research for its potential drug value. In recent years considerable research on its antimicrobial, antifungal, antioxidant and anti-inammatory effects, [6][7][8][9][10] and ability for selective/ preferential elimination of cancer cells has been undertaken.…”
Section: Introductionmentioning
confidence: 99%
“…The alkaloids were quantitatively estimated by the method described by Alfred0 Santos (8). Much variation was observed from sample to sample, but the average total alkaloidal content was 0.125y0.…”
Section: Methodsmentioning
confidence: 99%
“…Whole plant and seeds are the most extensively screened parts of A. mexicana. The alkaloids berberine and protopine (Santos and Adkilen 1932;Bose et al 1963;Chang et al 2003a) are the two major phytochemicals present in the A. mexicana. Whole plant: Phytochemicals identified from the whole plant include norsanguinarine, norchelerythrine, cryptopine, (À)-cheilanthifoline, (À)-β-scoulerine methohydroxide, and (À)-α-& β-stylopine methohydroxide (Haisova and Slavik 1975); isoquinolone: oxyhydrastinine (Hussain et al 1983); protopine: argemexicaine A, argemexicaine B, and allocryptopine; benzo(c) phenanthridines: (AE)-6-acetonyldihydrochelerythrine, norchelerythrine, O-methylzanthoxyline, sanguinarine, (AE)-6-acetonyldihydrosanguinarine, arnottianamide, (À)-angoline, and chelerythrine; protoberberine type alkaloids: (À)-tetrehydroberberine, dehydrocheilantifoline (Chang et al 2003a); alkaloids: tannic, caffeic, ferulic acids (Singh et al 2010a); quaternary isoquinoline alkaloids: dehydrocorydalmine, jatrorrhizine, columbamine, and oxyberberine (Singh et al 2010b); benzylisoquinoline alkaloid: argemexirine; protoberberine alkaloids: DL-tetrahydrocoptisine and dihydrocoptisine (Singh et al 2010c).…”
Section: Phytochemistrymentioning
confidence: 99%