The ACVD task force on canine atopic dermatitis (XIX): general principles of therapy

Olivry, Thierry; Sousa, Candace A.

doi:10.1016/s0165-2427(01)00347-6

Cited by 59 publications

(64 citation statements)

References 9 publications

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“…2,5,10 Using 150 EAU as the positive-negative determinants, the overall interlaboratory concordance of results for grasses, trees, and weeds was 94.2%, 94.5%, and 93.0%, respectively. These results are consistent within and among laboratories as well as with previously defined observations.…”

Section: Discussionmentioning

confidence: 97%

“…[3][4][5][10][11][12] The selection of allergens included in the allergen-specific therapeutic regimen relies on demonstration of immunoglobulin (Ig)E-mediated hypersensitivity by either intradermal skin testing or allergen-specific IgE serology. 1,2,6,10 Only recently has critical evaluation of some of the currently available tests been addressed. 7,8,13,14 In 2009, the performance characteristics of a monoclonal antibody cocktail-based enzyme-linked immunosorbent assay (macELISA) were described, and a preliminary interlaboratory evaluation between 2 laboratories that run this assay was provided.…”

Section: Introductionmentioning

confidence: 99%

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Proficiency monitoring of monoclonal antibody cocktail–based enzyme-linked immunosorbent assay for detection of allergen-specific immunoglobulin E in dogs

et al. 2015

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Abstract. The purpose of our study was to document the continued comparative proficiency of different laboratories that perform a monoclonal antibody-based enzyme-linked immunosorbent assay (macELISA) for detection of allergenspecific immunoglobulin (Ig)E in dogs. Replicate samples of 18 different sera pools were independently evaluated in a single blinded fashion by each of 16 different operators functioning in 10 different laboratories. The average intra-assay variance among reactive assay calibrators in all laboratories was 6.0% (range: 2.7-16.1%), while the average intralaboratory interassay variance was 7.5% (range: 3.9-10.9%). The overall interassay interlaboratory variance was consistent among laboratories and averaged 11.4% (range: 8.5-12.5%). All laboratories yielded similar profiles and magnitudes of responses for replicate unknown samples; dose response profiles observed in each of the laboratories were indistinguishable. Considering the positive or negative results, interassay interlaboratory concordance of results exceeded 90%. Correlation of optical density values between and among all laboratories was strong (r > 0.9, P < 0.001). Collectively, the results demonstrated that the macELISA for measuring allergen-specific canine IgE is reproducible, and documents that consistency of results can be achieved not only in an individual laboratory by differing operators but also among laboratories using the same monoclonal-based ELISA.

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Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Proficiency monitoring of monoclonal antibody cocktail–based enzyme-linked immunosorbent assay for detection of allergen-specific immunoglobulin E in dogs

et al. 2015

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“…90 Canine atopic dermatitis, which affects approximately 10% of all dogs, has an immunopathogenesis comparable to that of human atopic dermatitis. 62 Similar to their human atopic counterparts, who have high rates of secondary recurrent S. aureus and Malassezia spp.…”

Section: Antimicrobial Peptide Production In Atopic Dermatitismentioning

confidence: 99%

“…infections, 91 there are high rates of S. pseudintermedius and M. pachydermatis superinfections in canine atopic skin. 90 These cutaneous superinfections complicate management and further compromise the integrity of the skin barrier, and may be due in part to abnormally low AMP levels.…”

Section: Antimicrobial Peptide Production In Atopic Dermatitismentioning

confidence: 99%

Innate Immune Defense System of the Skin

Afshar

Gallo

2013

Advances in Veterinary Dermatology

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“…Chaque cas est particulier et une thérapeutique combinée, associant traitements des complications, traitement symptomatique, éviction allergénique et immunothérapie spéci-fique, est la clé du succès (OLIVRY et SOUSA, 2001b).…”

Section: Autres Traitementsunclassified

Dermatite atopique canine : actualités et aspects de pathologie comparée

Carlotti¹

2003

bavf

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Dermatite atopique canine : actualités et aspects de pathologie comparéeCanine atopic dermatitis : current data and comparative aspects Cet article présente les données actuelles concernant la dermatite atopique canine. L'étiopathogénie, les signes cliniques et le diagnostic, ainsi que le traitement et le suivi à long terme de la dermatose sont passés en revue. Lorsqu'elle se justifie, une comparaison avec la dermatite atopique humaine est effectuée. Mots

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The ACVD task force on canine atopic dermatitis (XIX): general principles of therapy

Cited by 59 publications

References 9 publications

Proficiency monitoring of monoclonal antibody cocktail–based enzyme-linked immunosorbent assay for detection of allergen-specific immunoglobulin E in dogs

Proficiency monitoring of monoclonal antibody cocktail–based enzyme-linked immunosorbent assay for detection of allergen-specific immunoglobulin E in dogs

Innate Immune Defense System of the Skin

Dermatite atopique canine : actualités et aspects de pathologie comparée

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