1980
DOI: 10.1002/em.2860020212
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The action of three anticlastogens on the induction of sister chromatid exchange by trenimon and 8‐hydroxyquinoline sulfate in human lymphocyte cultures

Abstract: The influence of the anticlastogens beta-aminoethylisothiouronium (AET), d,l-homocysteinethiolactone (HCT), and 1-cysteine (CYS) on the frequency of sister chromatid exchanges (SCEs) induced by the chromosome damaging chemicals Trenimon and 8-hydroxyquinoline sulfate (8-HQS), was investigated in human lymphocyte cultures. None of the anticlastogens significantly influenced the SCE rate, whereas in the same or previous experiments the chromosome-breaking effect of these clastogens was distinctly reduced by the … Show more

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Cited by 22 publications
(7 citation statements)
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“…The ClO2 contents in holding solution of all treatments were scavenged in two-four days after treatment. This study indicated that ClO2 4 µL・L (Knee, 2000;van Doorn et al, 1990), 폐기과정에서 환경오염을 유 발하고 (Florack et al, 1996), 8-HQS의 경우 인체에 유해하 여 상업적으로 사용이 제한되기도 한다 (Gebhart and Kappauf, 1980). 따라서 사용 후 환경오염을 유발하지 않는 친환경적 이면서도 인체에 유해하지 않고 가격이 저렴한 대체살균물 질이 요구되고 있다 (Florack et al, 1996).…”
unclassified
“…The ClO2 contents in holding solution of all treatments were scavenged in two-four days after treatment. This study indicated that ClO2 4 µL・L (Knee, 2000;van Doorn et al, 1990), 폐기과정에서 환경오염을 유 발하고 (Florack et al, 1996), 8-HQS의 경우 인체에 유해하 여 상업적으로 사용이 제한되기도 한다 (Gebhart and Kappauf, 1980). 따라서 사용 후 환경오염을 유발하지 않는 친환경적 이면서도 인체에 유해하지 않고 가격이 저렴한 대체살균물 질이 요구되고 있다 (Florack et al, 1996).…”
unclassified
“…On the other hand, TE has no antimutagenic effect against MMC induced SCEs; it seems obvious that it enhanced the effect of the mutagen MMC. However, some chemicals have been reported to show anticlastogenic effect in the formation of SCEs in human lymphocytes (Gebhart and Kappauf 1980;Renner 1984).…”
Section: Discussionmentioning
confidence: 99%
“…하는 문제로 상업적 이용이 점차 제한되면서 친환경 대체 물질에 대한 요구가 늘어나고 있다 (Gebhart and Kappauf, 1980 et al, 2010;van Doorn et al, 1990). 또한 절화의 수확 후 보존용액이나 선 별과정에서 세균 번식을 억제시키는데 유용한 것으로 알려 져 있다 (Knee, 2000;van Doorn et al, 1989).…”
Section: 하지만 이들 살균제들은 폐기 과정에서 환경오염을 유발unclassified