The acetabular labrum

Bsat, Suzan; Frei, Hanspeter; Beaulé, Paul E.

doi:10.1302/0301-620x.98b6.37099

Cited by 96 publications

(33 citation statements)

References 77 publications

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“…In contrast to the meniscus of the knee, little is known about calcification of the fibrocartilage of the hip, the acetabular labrum (ALH) and its relation to cartilage degeneration. Although the role of the acetabular labrum in hip joint pathology has recently gained much attention [ 19 , 20 ], knowledge about cellular mechanisms that govern labral function is scarce. It has recently been described that ALH cells appear to have a similar metabolic profile to meniscal cells [ 21 ], but to our knowledge there is only one study in which ALH calcification was analyzed in a larger cohort (106 hip joints in 66 individuals) by computed tomography (CT), finding a prevalence of 18% [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration

et al. 2018

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BackgroundMeniscal calcification is considered to play a relevant role in the pathogenesis of osteoarthritis of the knee. Little is known about the biology of acetabular labral disease and its importance in hip pathology. Here, we analyze for the first time the calcification of the acetabular labrum of the hip (ALH) and its relation to hip cartilage degeneration.MethodsIn this cross-sectional post-mortem study of an unselected sample of the general population, 170 ALH specimens and 170 femoral heads from 85 donors (38 female, 47 male; mean age 62.1 years) were analyzed by high-resolution digital contact radiography (DCR) and histological degeneration grade. The medial menisci (MM) from the same 85 donors served as an intra-individual reference for cartilage calcification (CC). Scanning electron microscopy (SEM), energy dispersive analysis (ED) and Raman spectroscopy were performed for characterization of ALH CC.ResultsThe prevalence of CC in the ALH was 100% and that in the articular cartilage of the hip (ACH) was 96.5%. Quantitative analysis revealed that the amount of ALH CC was higher than that in the ACH (factor 3.0, p < 0.001) and in the MM (factor 1.3, p < 0.001). There was significant correlation between the amount of CC in the fibrocartilage of the left and right ALH (r = 0.70, p < 0.001). Independent of age, the amount of ALH CC correlated with histological degeneration of the ALH (Krenn score) (r = 0.55; p < 0.001) and the ACH (Osteoarthritis Research Society International (OARSI), r = 0.69; p < 0.001). Calcification of the ALH was characterized as calcium pyrophosphate dihydrate deposition.ConclusionThe finding that ALH fibrocartilage is a strongly calcifying tissue is unexpected and novel. The fact that ALH calcification correlates with cartilage degeneration independent of age is suggestive of an important role of ALH calcification in osteoarthritis of the hip and renders it a potential target for the prevention and treatment of hip joint degeneration.

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Section: Introductionmentioning

confidence: 99%

Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration

et al. 2018

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“…It is known that acetabular labrum contributes fundamentally to hip stability by its suctioning function in neutral hip anatomic position. 31 In this position, the middle part of the labrum is primarily loaded, leading to a remarkable mechanical wear. This biomechanical conclusion may rationalize the presence of abundant FNEs in the middle part of acetabular labrum.…”

Section: Discussionmentioning

confidence: 99%

Acetabular labrum of hip joint in osteoarthritis: A qualitative original study and short review of the literature

Kapetanakis

Dermon

Gkantsinikoudis

et al. 2017

Journal of Orthopaedic Surgery

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Differentiation of the distribution pattern of MRs and FNEs in acetabular labrum of hip joint is remarkable between normal patients and patients with severe OA. The abundance of FNEs in the middle part of the pathologic labrum is mainly responsible for the observed discrimination. A "conversion" of MRs to FNEs may occur during OA progression, modulating therefore this pattern as well as the upcoming clinical manifestations.

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“…Its tensile modulus, a measure of its stiffness and tensile strength to stretching, is six times greater compared to rubber. 11 This feature is also important for its function as a hip suction seal. On the other hand, the acetabular labrum has no important role in supporting the axial load of the hip.…”

Section: Pathophysiologymentioning

confidence: 99%

Impacto femoroacetabular e lesão do lábio acetabular - Parte 1: Fisiopatologia e biomecânic

Ejnisman

Júnior

Queiroz

et al. 2020

Rev Bras Ortop (Sao Paulo)

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ResumoO impacto femoroacetabular (IFA) é uma importante causa de dor no quadril, e a principal etiologia da osteoartrose do quadril no jovem. O IFA é caracterizado por alterações sutis da anatomia do acetábulo e do fêmur proximal que podem causar lesões do complexo condrolabial. O lábio é uma estrutura fibrocartilaginosa essencial na estabilidade articular. Três tipos de IFA são descritos: came (onde há uma anesfericidade da cabeça femoral), pincer (onde há uma sobrecobertura acetabular) e misto (que apresenta características de ambos). A etiologia do IFA está relacionada com características genéticas e ambientais. O conhecimento desta doença e sua fisiopatologia é essencial para o tratamento de pacientes que apresentam dor no quadril.

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The acetabular labrum

Abstract: The acetabular labrum plays a critical role in hip function and maintaining and restoring its function during surgical intervention remain an essential goal. Cite this article: Bone Joint J 2016;98-B:730-5.

Cited by 96 publications

References 77 publications

Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration

Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration

Acetabular labrum of hip joint in osteoarthritis: A qualitative original study and short review of the literature

Impacto femoroacetabular e lesão do lábio acetabular - Parte 1: Fisiopatologia e biomecânic

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