The accuracy of noninvasive total hemoglobin measurement in critically ill patients

Oishi, Rieko; Hasegawa, Masumi; Hakozaki, Takahiro; Obara, Shinju; Isosu, Tsuyoshi; Murakawa, Masahiro

doi:10.1016/j.bjane.2019.05.002

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Brazilian Journal of Anesthesiology (English Edition)

2019

DOI: 10.1016/j.bjane.2019.05.002

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The accuracy of noninvasive total hemoglobin measurement in critically ill patients

Rieko Oishi

Masumi Hasegawa

Takahiro Hakozaki

et al.

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2022

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Progressive evaluation in spectroscopic sensors for non-invasive blood haemoglobin analysis—a review

Kumar¹,

Dogra²,

Kumar³

2022

Physiol. Meas.

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Frequent monitoring of haemoglobin concentration is highly recommended by physicians to diagnose anaemia and polycythemia Vera. Moreover, Some other conditions also demand assessment of haemoglobin, and these conditions are blood loss, before blood donation, during pregnancy, preoperative, perioperative and postoperative conditions. Cyanmethaemoglobin/haemiglobincyanide method, portable haemoglobinometers and haematology analyzers are few standard methods to diagnose mentioned ailments. However, discomfort, delay and risk of infection are typical limitations of traditional measuring solutions. These limitations create the necessity to develop a non-invasive haemoglobin monitoring technique for a better lifestyle. Various methods and products are already developed and popular due to their non-invasiveness; however, invasive solutions are still considered as the reference standard method. Therefore, this review summarizes the attributes of existing non-invasive solutions. These attributes are finalized as brief details, accuracy, optimal benefits, and research challenges for exploring potential gaps, advancements and possibilities to consider as futuristic alternative methodologies. Non-invasive total haemoglobin assessing techniques are mainly based on optical spectroscopy (reflectance/transmittance) or digital photography or spectroscopic imaging in spot check/continuous monitoring mode. In all these techniques, we have noticed that there is a need to consider different light conditions, motion artefacts, melanocytes, other blood constituents, smoking and precise fixing of the sensor from the sensing spot for exact formulation. Moreover, based on careful and critical analysis of outcomes, none of these techniques or products is used independently or intended to replace invasive laboratory testing. Therefore there is a requirement for a more accurate technique that can eliminate the requirement of blood samples and likely end up as a reference standard method.

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Progressive evaluation in spectroscopic sensors for non-invasive blood haemoglobin analysis—a review

Kumar¹,

Dogra²,

Kumar³

2022

Physiol. Meas.

View full text Add to dashboard Cite

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NIR-based Sensing System for Non-invasive Detection of Hemoglobin for Point-of-care Applications

Kumar

Dogra

Shaw

et al. 2022

CMIR

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Background: Hemoglobin is an essential biomolecule for the transportation of oxygen, therefore, its assessment is also important to be done frequently in numerous clinical practices. Traditional invasive techniques have concomitant shortcomings, such as time delay, the onset of infections, and discomfort, which necessitate a non-invasive hemoglobin estimation solution to get rid of these constraints in health informatics. Currently, various techniques are underway in the allied domain, and scanty products are also feasible in the market. However, due to the low satisfaction rate, invasive solutions are still assumed as the gold standard. Recently introduced technologies effectively evolved as optical spectroscopy and digital photographic concepts on different sensing spots, e.g., fingertip, palpebral conjunctiva, bulbar conjunctiva, and fingernail. Productive sensors develop more than eight wavelengths to compute hemoglobin concentration and four wavelengths to display only Hb-index (trending of hemoglobin) either in disposable adhesive or reusable cliptype sensor’s configuration. Objective: This study aims at an optimistic optical spectroscopic technique to measure hemoglobin concentration and conditional usability of non-invasive blood parameters’ diagnostics at point-ofcare. Methods: Two distinguishable light emitting sources (810 nm and 1300 nm) are utilized at isosbestic points with a single photodetector (800-1700 nm). With this purpose, reusable finger probe assembly is facilitated in transmittance mode based on the newly offered sliding mechanism to block ambient light. Results: Investigation with proposed design presents correlation coefficients between reference hemoglobin and every individual feature, a multivariate linear regression model for highly correlated independent features. Moreover, principal component analytical model with multivariate linear regression offers mean bias of 0.036 and -0.316 g/dL, precision of 0.878 and 0.838 and limits of agreement from -1.685 to 1.758 g/dL and -1.790 to 1.474 g/dL for 18 and 21 principal components, respectively. Conclusion: The encouraging readouts emphasize favorable precision; therefore, it is proposed that the sensing system is amenable to assess hemoglobin in settings with limited resources and strengthening future routes for the point of care applications.

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The accuracy of noninvasive total hemoglobin measurement in critically ill patients

Cited by 2 publications

References 2 publications

Progressive evaluation in spectroscopic sensors for non-invasive blood haemoglobin analysis—a review

Progressive evaluation in spectroscopic sensors for non-invasive blood haemoglobin analysis—a review

NIR-based Sensing System for Non-invasive Detection of Hemoglobin for Point-of-care Applications

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