The Acceptance Rate Toward COVID-19 Vaccine in Africa: A Systematic Review and Meta-analysis

Abstract

Background: The Coronavirus Disease 2019 (COVID-19) pandemic remains serious public issue. COVID-19 vaccine is a vital strategy to prevent this critical pandemic. However, unwillingness to take this vaccine are key barriers to manage the COVID-19 pandemic. The control of this pandemic will depend principally on the people acceptance of COVID-19 vaccine. Therefore, this systematic review and meta-analysis was intended to determine the acceptance rate toward COVID-19 vaccine in Africa. Methods: African Journals OnLine, PubMed, Cochrane Review, HINARI, EMBASE, Google Scholar, Web of Science, and Scopus were used to retrieve related articles. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were used for this study. Random-effect model, a funnel plot, Egger’s test, I2 statistic, subgroup analysis was done. The study was performed by using a STATA version 11 statistical software. Results: A total of 22 studies with 33,912 study participants were included in this systematic review and meta-analysis. From this finding, the pooled prevalence of acceptance toward COVID-19 vaccine among adults in Africa was 48.93% (95% CI: [39.49, 58.37]). The subgroup analysis revealed that the pooled prevalence of COVID-19 vaccine acceptance among adults in Africa was highest (66.03%, 95% CI [62.84, 69.22]) in Southern Africa, and Lowest (24.28%, 95% CI [3.26, 45.30]) in Northern Africa. Conclusion: This study showed that the estimate of the pooled prevalence of acceptance toward COVID-19 vaccine among adults in Africa was very low. All concerned bodies should be actively involved to improve the acceptance rate of COVID-19 vaccine.

COVID-19 vaccination in Nigeria: A rapid review of vaccine acceptance rate and the associated factors

“…This finding is consistent with surveys that were conducted in most other African countries like Ethiopia (31.4%), Ghana (39.3%), DR Congo (55.9%), and Uganda (53.6%). However, there were substantial differences when compared with studies conducted in Egypt (13.5%), and South Africa (63.3%) [ 18 ]. This variation could have resulted from underlying contextual differences, including divergence in the demographic and social features of the different survey populations.…”

“…COVID-19 acceptance rates worldwide and in Africa have been surveyed and reported in previous studies. The proportion of willingness to accept COVID-19 vaccination drawn from pooled prevalence acceptance rates across the world has been rated below 60% [ 17 ] and 48.93% across Africa [ 18 ]. However, some of the problems were not explored.…”

Willingness to receive the COVID-19 vaccine and associated factors among residents of Southwestern Ethiopia: A cross-sectional study

“…Before the COVID-19 pandemic, the World Health Organization listed vaccine hesitancy as one of the ten global threats to public health. 12 Different research and systematic reviews were conducted on the Willingness to Get the COVID-19 Vaccine and the Factors That Influence It. Knowing the amount of desire to get the COVID-19 vaccine and the factors that influence it would provide useful information and guidance for clinical deployment and intervention development.…”

Patients’ Acceptance of COVID-19 Vaccine: Implications for Patients with Chronic Disease in Low-Resource Settings

“…4 It has been estimated that the pooled prevalence of acceptance rates toward the COVID-19 vaccine among patients in Africa is very low. 9 Women were found to be less willing to accept the vaccine than men, while people under the age of 25 years and less well-educated respondents were marginally more willing to take the vaccine than their respective comparator groups. 10,11 Besides vaccine efficacy and safety, vaccine acceptance among the general population plays a paramount role in the successful eradication of the virus.…”