The absence of focal choroidal excavation in children and adolescents without retinal or choroidal disorders or ocular trauma

Ka, Park; Sy, Oh

doi:10.1038/eye.2015.6

Cited by 18 publications

(9 citation statements)

References 6 publications

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“…However, with the extensive application of OCT and OCT angiography, researchers have found that acquired forms of FCE may exist, as they have appeared with many clinical conditions ranging from pachychoroid spectrum diseases, white dot syndrome, and macular dystrophy. Park et al 3 also reported that among 1,697 eyes from 858 children and young adults, only three eyes were identified with FCE. The low incidence of FCE in young patients suggests that FCE is most likely acquired during adulthood.…”

mentioning

confidence: 99%

Correlation Between Focal Choroidal Excavation and Underlying Retinochoroidal Disease

Gan¹,

Ji²,

Zuo³

et al. 2022

Retina

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Supplemental Digital Content is Available in the Text. We evaluated focal choroidal excavation in eyes with diverse chorioretinal diseases. Focal choroidal excavations show close relationship with the underlying chorioretinal diseases. Impairment or tissue loss of the outer retina and inner choroid and disruption of the balance of intraocular pressure and choroidal pressure might be common mechanisms of focal choroidal excavation formation.

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confidence: 99%

Correlation Between Focal Choroidal Excavation and Underlying Retinochoroidal Disease

Gan¹,

Ji²,

Zuo³

et al. 2022

Retina

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“…Some investigators speculated that FCE may be a congenital posterior segment malformation; in contrast, others mentioned that FCE found in adults is more likely to involve an acquired type. 1 , 2 , 10 In the posterior region of the eye, collagenous layers include the internal limiting membrane, Bruch's membrane, and the sclera. Scleral weakness may be associated with posterior staphyloma.…”

Section: Discussionmentioning

confidence: 99%

Focal choroidal excavation disappearing after successful treatment of type 2 choroidal neovascularization with intravitreal aflibercept

Sato

Yasukawa

Hayashi

2021

American Journal of Ophthalmology Case Reports

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Purpose To report a case with focal choroidal excavation (FCE) accompanied by type 2 choroidal neovascularization (CNV), in which the CNV was successfully treated with intravitreal aflibercept, after which the FCE was no longer detectable. Observations A conforming type of FCE was detected in the left eye of a 34-year-old Japanese man who visited our hospital for a second opinion regarding treatment for his right eye. Three months later, type 2 CNV developed in the region corresponding to the FCE in the left eye. After treatment with intravitreal aflibercept, the CNV disappeared, and FCE was no longer detected. No recurrence has been observed in the 12 months following the treatment. Conclusions and Importance Although the etiology of FCE has not been fully elucidated, we discussed the mechanisms underlying its occurrence, its association with CNV, and the disappearance of both conditions after treatment.

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“…Although many researchers have proposed various pathologies for FCE, the exact pathology of FCE remains unclear. Recently, it was reported that FCE was only detected in 3 out of 1,697 eyes of children and young adults, with this low prevalence suggesting that most FCE may be acquired [ 11 ]. However, there have been a few studies that have reported on the developmental process of acquired FCE.…”

Section: Discussionmentioning

confidence: 99%

A Case of Focal Choroidal Excavation Development Associated with Multiple Evanescent White Dot Syndrome

Matsubara

Uchiyama

Suzuki

et al. 2018

Case Rep Ophthalmol

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Focal choroidal excavation (FCE) is described as an excavated lesion of the choroid that can be detected by optical coherence tomography (OCT). While the exact pathogenesis of FCE remains unclear, it has been proposed in some cases that there is an association with the inflammation in the outer retina. We present a case of FCE development that was detected by spectral domain OCT (SD-OCT) and found to be associated with multiple evanescent white dot syndrome (MEWDS). A 40-year-old Japanese woman was diagnosed with MEWDS based on multiple white dots observed from the posterior pole to the midperiphery, along with yellow granularity in the fovea. SD-OCT revealed separation between the retinal pigment epithelium (RPE) and Bruch’s membrane (BM) and discontinuations of the ellipsoid zone, RPE, and BM. At 4 weeks after onset, several of the white dots disappeared, the yellow granularity in the fovea became small, and we detected nonconforming choroidal excavation under the central fovea. The choroidal excavation gradually deepened and changed to a conforming pattern. These findings suggest that the degree of the impairment caused by inflammation and the plasticity of the BM and RPE complex may be associated with different types of acquired FCE.

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The absence of focal choroidal excavation in children and adolescents without retinal or choroidal disorders or ocular trauma

Cited by 18 publications

References 6 publications

Correlation Between Focal Choroidal Excavation and Underlying Retinochoroidal Disease

Correlation Between Focal Choroidal Excavation and Underlying Retinochoroidal Disease

Focal choroidal excavation disappearing after successful treatment of type 2 choroidal neovascularization with intravitreal aflibercept

A Case of Focal Choroidal Excavation Development Associated with Multiple Evanescent White Dot Syndrome

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