The ABCD grading system in assessment of corneal cross-linking effect in keratoconus with different cone locations

Krolo, Ivan; Kasumović, Aida; Matoc, Ines; Sabol, Ivan; Radman, Ivana; Ratkovic, Mirko

doi:10.1016/j.optom.2021.09.002

Cited by 1 publication

(2 citation statements)

References 36 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the literature, only a few studies evaluated the applicability of the ABCD staging system in monitoring the efficacy of the standard procedure. In contrast, only one recently published retrospective study investigated its utility in evaluating accelerated protocols and compared the effectiveness of different protocols regarding the ABCD grading system [ 8 , 39 , 40 , 41 , 42 , 43 ]. Danesh and coauthors showed no significant changes in parameters A and D, while parameters B and C significantly increased one year after conventional CXL [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

“…Krolo et al investigated the efficacy of the standard protocol according to the cone location, central or peripheral. They showed no significant changes in parameter A and a significant increase in parameters B and C in the 12-month post-treatment period [ 41 ]. Parameter D initially increased and returned to the preoperative value one year after the standard CXL procedure.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Short-Term Effect of Conventional Versus Accelerated Corneal Cross-Linking Protocol on Corneal Geography and Stability

Vidas Pauk,

Jandroković,

Lešin Gaćina

et al. 2023

Medicina

View full text Add to dashboard Cite

Purpose: To determine the 6-month effect of conventional (CXL30) and accelerated cross-linking with a UVA intensity of 9 mW/cm2 (CXL10) on corneal stability and to investigate whether there was a difference in ABCD grading system parameters regarding the two different procedures. Methods: Twenty-eight eyes of 28 patients with a documented keratoconus (KN) progression were included. Patients were selected to undergo either epi off CXL30 or CXL10. At the baseline and the follow-up visits after one (V1), three (V2), and six months (V3), the patients underwent complete ophthalmic examination and corneal tomography. Results: In the CXL30 group, all the parameters from the ABCD grading system significantly changed from baseline to V3; parameter A decreased (p = 0.048), B and C increased (p = 0.010, p < 0.001), and D decreased (p < 0.001). In the CXL10 group, there were no changes in parameters A (p = 0.247) and B (p = 0.933), though parameter C increased (p = 0.001) and D decreased (p < 0.001). After an initial decline after one month, visual acuity (VA) recovered on V2 and V3 (p < 0.001), and median maximal keratometry (Kmax) decreased in both groups (p = 0.001, p = 0.035). In the CXL30 group, there were significant changes in other parameters; average pachymetric progression index (p < 0.001), Ambrósio relational thickness maximum (ARTmax) (p = 0.008), front and back mean keratometry (p < 0.001), pachymetry apex (PA) (p < 0.001), and front elevation (p = 0.042). However, in the CXL10 group, there were significant changes only in ARTmax (p = 0.019) and PA (p < 0.001). Conclusion: Both epi-off CXL protocols showed similar short-term efficacy in improving VA and Kmax, halting the progression of KN, and both similarly changed tomographic parameters. However, the conventional protocol modified the cornea more significantly.

show abstract