Thaumatin-like pathogenesis-related proteins are antifungal

Vigers, Alison J.; Wiedemann, Sabine; Roberts, Walden K.; Legrand, Michel; Selitrennikoff, Claude P.; Fritig, Bernard

doi:10.1016/0168-9452(92)90074-v

Cited by 196 publications

(109 citation statements)

References 31 publications

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“…We also found a high baseline expression for cecropin in Tribolium castaneum , indicating that these AMPs might be important for prevention of infection in adults. Both thaumatins and tenecin 3 are antifungal proteins (Jung et al, 1995;Lee et al, 1996;Vigers et al, 1992) and were not expected to be induced upon bacterial infection. They are however expressed at much higher levels in adults than in eggs.…”

Section: Discussionmentioning

confidence: 99%

Endogenous egg immune defenses in the yellow mealworm beetle (Tenebrio molitor)

Jacobs

Gallagher

Evison

et al. 2017

Developmental & Comparative Immunology

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In order to survive microbe encounters, insects rely on both physical barriers as well as local and systemic immune responses. Most research focusses on adult or larval defenses however, whereas insect eggs are also in need of protection. Lately, the defense of eggs against microbes has received an increasing amount of attention, be it through endogenous egg defenses, trans-generational immune priming (TGIP) or parental investment. Here we studied the endogenous immune response in eggs and adults of Tenebrio molitor. We show that many immune genes are induced in both adults and eggs. Furthermore, we show that eggs reach comparable levels of immune gene expression as adults. These findings show that the eggs of Tenebrio are capable of an impressive endogenous immune response, and indicate that such inducible egg defenses are likely common in insects.

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Section: Discussionmentioning

confidence: 99%

Endogenous egg immune defenses in the yellow mealworm beetle (Tenebrio molitor)

Jacobs

Gallagher

Evison

et al. 2017

Developmental & Comparative Immunology

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“…The phytopathogenic fungi studied in this work showed different susceptibilities when assayed with equal amounts of P23, ranging from considerable inhibition to almost complete insensitivity. This differential sensitivity indicates that, as suggested before (Vigers et al, 1992), the particular features of the different fungi (e.g. cell wall components or membrane receptors) condition their differential susceptibility to P23.…”

Section: Discussionmentioning

confidence: 99%

“…The recently reported in vitro antifungal activity of osmotin-like proteins (Woloshuk et al, 1991) and other thaumatinlike proteins (Vigers et al, 1991(Vigers et al, , 1992 shed new light on our understanding of the biological role of this protein family. As we showed previously (Rodrigo et al, 1991), viroid infection of tomato plants results in the accumulation of a thaumatin-like PR protein (P23), which we identified as the salt stress-induced tomato osmotin NP24 because of the almost identical peptide sequence displayed by these two proteins.…”

Section: Discussionmentioning

confidence: 99%

“…102,. 1993 that thaumatin-like proteins are antifungal (Vigers et al, 1991(Vigers et al, , 1992). When P23 was tested for antifungal activity, this viroid-induced PR protein inhibited the growth of a number of phytopathogenic fungi, although with different inhibitory activities.…”

Section: Antifungal Activity Of the Viroid-lnduced Tomato Pr P23 Proteinmentioning

confidence: 99%

“…In view of recent reports conceming the antifungal activity of osmotins and other thaumatin-like proteins (Vigers et al, 1991(Vigers et al, , 1992Woloshuk et al, 1991), we also evaluated the antifungal activity of P23. In addition, several cDNA clones encoding for tomato P23 were isolated, and the complete sequence of one of them (pTCP23.1) is presented.…”

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confidence: 99%

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