Thalassemia in Iran

Abolghasemi, Hassan; Amid, Ali; Zeinali, Sirous; Radfar, Mohammad Hadi; Eshghi, Peyman; Rahiminejad, Mohammad Saeid; Ehsani, Mohammad Ali; Najmabadi, Hossein; Akbari, Mohammad Taghi; Afrasiabi, Abdolreza; Akhavan‐Niaki, Haleh; Hoorfar, Hamid

doi:10.1097/mph.0b013e3180437e02

Cited by 158 publications

(70 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has also reported that over 70% of thalassaemia patients in Iran are older than 10 years [29]. In Iran, the prevalence of anti-HCV in hemophiliac is from 15.65% to 76.7% in patients from various geographical regions [30]. The majority of positive cases among hemophiliacs refl ect treatment with unscreened or not effi ciently inactivated blood products in the past.…”

Section: Discussionmentioning

confidence: 99%

Identification of HCV genotypes in HCV infected blood donors

Sharifi¹,

Shooshtari²,

Kermani³

2010

Indian J Microbiol

View full text Add to dashboard Cite

HCV infection is a leading cause of chronic liver disease, including cirrhosis of the liver. There are at least six major genotypes and more than 50 subtypes of HCV. The prevalence and distribution of HCV genotypes depend on geographical location. The aim of this study was to identify and compare the HCV genotypes in HCV infected blood donors and patients. In this cross-sectional study, 167 serum samples from 103 blood donors and 64 patients with hepatitis C were investigated for HCV genotypes. HCV genotyping was carried out using type-specifi c primers from the core region of the viral genome. The highest frequency was for genotype 1a, with 53 and 34 (51.5% versus 53.1%) of subjects in blood donors and patients respectively. Genotype 3a and 1b were the other frequent genotypes with 4 and 16 (3.9% versus 25%) and 39 and 10 (37.9% versus 15.6%) subjects, respectively. There was not any statistical signifi cant association between the place of infection of the patients and genotype. The results of this study indicate that the distribution of genotypes in the two populations was similar. The dominant HCV genotypes between blood donors and patients were 1a, 3a and 1b respectively.

show abstract

Section: Discussionmentioning

confidence: 99%

Identification of HCV genotypes in HCV infected blood donors

Sharifi¹,

Shooshtari²,

Kermani³

2010

Indian J Microbiol

View full text Add to dashboard Cite

show abstract

“…Iran is located on the "Thalassemia Belt" in the Eastern Mediterranean region of World Health Organization (WHO). Iran is indeed one of most important countries with high prevalence of β-thalassemia major (Ghotbi & Tsukatani, 2005;Rezaee et al, 2012;Abolghasemi et al, 2007). Although the exact prevalence rates of β-thalassemia major in Iran are not available; however, it is estimated that prevalence rate of β-thalassemia major carriers in Iran is about 4% which is significantly higher than the average β-thalassemia major gene prevalence (1.5%) of world (Miri et al, 2013).…”

Section: Introductionmentioning

confidence: 93%

Caregiver Burden and Social Support in Mothers with β-Thalassemia Children

Mashayekhi¹,

Jozdani²,

Chamak³

et al. 2016

GJHS

View full text Add to dashboard Cite

Background: In our knowledge, there was no available information on social support and caregiver's burden among parents of thalassemic children. Aim:To examine caregiver's burden and social support in mothers of thalassemic children, this study was conducted. Methods:This cross-sectional study was conducted from July to October 2013 in Jiroft Thalassemic Center (JTC) in southeast of Iran. To assess the caregiver's burden and social support, caregiver burden scale and Norbeck social support questionnaire was used respectively. Results:There was a response rate of 98% (160 out of 163 mothers were participated). Generally, 51.5% and 49.5% of mothers reported low and high level of social support, respectively. In term of caregiver's burden, 20%, 29% and 51% of mothers reported high, moderate and low level of burden, respectively. There was no significant correlation between mean score of caregiver's burden and mean score of social support. Conclusion:Our study showed that social support of Iranian mothers with thalassemic children is low. In addition, caregiver's burden among this group of mothers is high. Further research is recommended to prepare more evidence in this regard.

show abstract

“…Based on different studies, the prevalence of HCV infection in patients with thalassemia is approximately 4.4% -85% in the world (11,12). The incidence of HCV infection in children with β-thalassemia major in Egypt is reported 40% (13). In another study in Pakistan, the prevalence of HBV and HCV infections in patients with thalassemia was reported 1.7% and 35%, respectively (14).…”

Section: Introductionmentioning

confidence: 99%