Tetraphenylethylene-Based AIE-Active Probes for Sensing Applications

Abstract

This Review provides a comprehensive analysis of recent development in the field of aggregation-induced emission (AIE)-active tetraphenylethylene (TPE) luminophores and their applications in biomolecular science. It begins with a discussion of the diverse range of structural motifs that have found particular applications in sensing, and demonstrates that TPE structures and their derivatives have been used for a diverse range of analytes such as such as H, anions, cations, heavy metals, organic volatiles, and toxic gases. Advances are discussed in depth where TPE is utilized as a mechanoluminescent material in bioinspired receptor units with specificity for analytes for such as glucose or RNA. The rapid advances in sensor research make this summary of recent developments in AIE-active TPE luminophores timely, in order to disseminate the advantages of these materials for sensing of analytes in solution, as well as the importance of solid and aggregated states in controlling sensing behavior.

Selective Fluorescence Turn‐On Sensing of Phosphate Anion in Water by Tetraphenylethylene Dimethylformamidine

“…Some of them show valuable application prospect in monitoring, analysis, imaging of ions . However, research work on anion sensors based on AIE effect was relatively little.…”

“…[9][10][11][12][13] Up to now,al arge number of sensors based on AIEgens have been developed. [14][15][16][17][18][19][20] Some of them show valuablea pplication prospecti nm onitoring,a nalysis, imaging of ions. [16][17][18][19][20] However,r esearch work on anion sensors based on AIE effect was relatively little.…”

“…[14][15][16][17][18][19][20] Some of them show valuablea pplication prospecti nm onitoring,a nalysis, imaging of ions. [16][17][18][19][20] However,r esearch work on anion sensors based on AIE effect was relatively little. Gao et al reported that monoimidazolium with AIE effect could selectively recognize H 2 PO 4À in acetonitrile, but could not do in water.…”

Selective Metal‐Ion Detection and Activatable Photosensitization Properties of a Tetraphenylethylene‐Based Salicylideneimine

“…Tetraphenylethylene was selected as the backbone of the chemosensor because of its established luminescence properties, ease of synthesis and the possibility of multiple functionalization . The chemosensor ( 4 ) was synthesized in three steps starting from tetraphenylethylene 1 (Figure ).…”

Influence of Odd and Even Alkyl Chains on Supramolecular Nanoarchitecture via Self-Assembly of Tetraphenylethylene-Based AIEgens

“…These AIE fluorophores have been employed to construct self-assembled fibers, nanowires, microrods, microtubes, hollow microspheres, microparticles, microblocks, microparticles, bird nest-like and flower-like structures, and helical morphologies in tetrahydrofuran (THF)/water solvent systems [14][15][16][17][18][19][20][21][22][23][24][25]. These molecular assemblies solvent systems [14][15][16][17][18][19][20][21][22][23][24][25]. These molecular assemblies derive from weak non-covalent interactions, such as hydrogen bonding, electrostatic interactions, π-π stacking, van der Waals forces and solvophobic interactions.…”