Tetranactin, a New Miticidal Antibiotic. III. Miticidal and Other Biological Properties1

Sagawa, Takao; Hirano, Seiji; Takahashi, Hironobu; Tanaka, Nobuhiko; Oishi, Hideo; Ando, Kiyoshi; Togashi, Kunihiko

doi:10.1093/jee/65.2.372

Cited by 26 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the exception of nonactin, they exhibit, in addition to the antibacterial and antifungal activity, also remarkable acaridical, insecticidal, coccidiostatic, and anthelminthic effects [5,8,9]. Besides, the macrotetrolide antibiotics are very potent uncouplers of oxidative phosphorylation in mitochondria [10].…”

Section: Introductionmentioning

confidence: 99%

Experimental and theoretical study on interaction of the silver cation with nonactin

Makrlík

Vaňura

2015

Molecular Physics

View full text Add to dashboard Cite

From extraction experiments and γ -activity measurements, the extraction constant corresponding to the equilibrium Ag + (aq) + 1 · Na + (nb) → ← 1 · Ag + (nb) + Na + (aq) occurring in the two-phase water-nitrobenzene system (1 = nonactin, aq = aqueous phase, nb = nitrobenzene phase) was evaluated as log K ex (Ag + , 1 · Na + ) = 0.6 ± 0.1. Furthermore, the stability constant of the 1 · Ag + complex in nitrobenzene saturated with water was calculated for a temperature of 25 • C: log β nb (1 · Ag + ) = 6.6 ± 0.2. Finally, employing quantum mechanical calculations, the most probable structure of the cationic complex species 1 · Ag + was derived. In the resulting complex, having a tennis-ball-seam conformation with the C 2 symmetry, the 'central' cation Ag + is bound by eight relatively strong bonding interactions to eight oxygen atoms of the parent nonactin ligand. The interaction energy of the considered 1 · Ag + complex was found to be -468.5 kJ/mol, confirming also the formation of this cationic species.

show abstract

Section: Introductionmentioning

confidence: 99%

Experimental and theoretical study on interaction of the silver cation with nonactin

Makrlík

Vaňura

2015

Molecular Physics

View full text Add to dashboard Cite

show abstract

“…With the exception of nonactin, they exhibit, in addition to antibacterial and antifungal activity, also remarkable acaricidal, insecticidal, coccidiostatic, and anthelminthic effects [5,8,9]. Besides, the macrotetrolide antibiotics are very potent uncouplers of oxidative phosphorylation in mitochondria [10].…”

Section: Introductionmentioning

confidence: 99%

Experimental and theoretical study on the complexation of the strontium cation with nonactin

Makrlík

Toman

Vaňura

2013

Journal of Molecular Structure

View full text Add to dashboard Cite

“…1984). Recently, T. cinnabarinus have developed serious resistance to many chemical pesticides such as fenpyromimate, pyridaben, tebufenpyrad and pyrimidifen (Granham et al 1985;Grosscurt et al 1988; Gu et al 2000;Sagawa et al 1972;Shen 1999). Since T. cinnabarinus are highly reproductive mites and have short generation time, they can build up their population very fast.…”

Section: Introductionmentioning

confidence: 99%

Identification of Acarcidal Compounds in Inula japonica Extracts against Tetranychus cinnabarinus

Duan

et al. 2012

Advances in Intelligent and Soft Computing

View full text Add to dashboard Cite

Abstract. In this study, we aimed to identify acaricidal compounds in Inula japonica against Tetranychus cinnabarinus. Here, I. japonica petroleum-ether extracts were found toxic to T. cinnabarinus with a LC50 value of 1.18 mg/ml. Silica gel column chromatography was used to further separate acaricidal components from I. japonica petroleum-ether extracts. Contact toxicity data showed that 17 out of 38 fractions groups had mite mortality rates above 50%, 9 fraction groups above 60 %, and fractions groups G5, G7 and G15 even above 80 % at a concentration of 2 mg/ml. The major vital compounds in the bioactive fraction groups were identified by GC/MS, and four compounds, namely β-Sitosterol (1), Stigmasterol (2), Lupeol (3), and α-Amyrin (4) were determined to have acaricidal activity to Tetranychus cinnabarinus.

show abstract

Tetranactin, a New Miticidal Antibiotic. III. Miticidal and Other Biological Properties1

Cited by 26 publications

References 0 publications

Experimental and theoretical study on interaction of the silver cation with nonactin

Experimental and theoretical study on interaction of the silver cation with nonactin

Experimental and theoretical study on the complexation of the strontium cation with nonactin

Identification of Acarcidal Compounds in Inula japonica Extracts against Tetranychus cinnabarinus

Contact Info

Product

Resources

About