Tetracaine 0.5% eyedrops with or without lidocaine 2% gel in topical anesthesia for cataract surgery

Tsoumani, Anthoula T; Asproudis, Ioannis; Damigos, D.

doi:10.2147/opth.s11755

Cited by 13 publications

(8 citation statements)

References 19 publications

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“…Tsoumani et al . reported a VAS score of 4.19 ± 2.321) in patients who underwent cataract surgery with 0.5% tetracaine 10. Soliman et al .…”

Section: Discussionmentioning

confidence: 99%

A single drop of 0.5% proparacaine hydrochloride for uncomplicated clear corneal phacoemulsification

Joshi¹

2013

Middle East Afr J Ophthalmol

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Purpose:The purpose of this study was to compare the efficacy of a single drop of 0.5% proparacaine hydrochloride in uncomplicated cataract surgery with phacoemulsification.Materials and Methods:Two hundred and ninety five patients scheduled for the phacoemulsification were divided into 2 groups based on the anesthetic agents they were to receive: 146 patients who received a single drop of 0.5% proparacaine 2 min before the start of the surgery (proparacaine group) and; 149 patients who received supplementation of 0.5% intracameral preservative free xylocaine (xylocaine group). A single surgeon performed all surgeries. Intraoperative and post-operative pain scores were evaluated on a visual analog scale. The surgeon noted his subjective impression of corneal clarity, discomfort while performing the surgery any supplemental anesthesia required and intraoperative complications. An anesthetist noted vital parameters and the need for intravenous sedation. Total surgical time was noted. Comparison of parameters was performed with the Chi-square test, and A P value less than 0.05 was considered as statistically significant.Results:No statistically significant difference was seen in the intraoperative (P = 0.24) and post-operative (P = 0.164) pain scores between groups. There was no pain (0 score) in 41.8% of patients in the proparacaine group and 46.3% of patients in the xylocaine group. The average surgical time (P = 0.279) and surgeon discomfort (P = 0.07) were not statistically significantly different between groups. No patients required supplemental anesthesia. There were no surgical complications that could compromise the visual outcome. An equal number of patients in both groups preferred same type of anesthetic technique for the fellow eye cataract surgery (89.11% for the proparacaine group and 90.18% for the xylocaine group). No patients in either group had changes in vital parameters or required intravenous sedation.Conclusion:A single drop pre-operatively, of proparacaine hydrochloride was comparable to the intracameral supplementation of preservative free xylocaine for phacoemulsification in uncomplicated cataract surgery without compromising the visual outcome. However, we recommend individualizing the anesthetic technique according to the requirements of the surgeon.

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“…Tsoumani et al . reported a VAS score of 4.19 ± 2.321) in patients who underwent cataract surgery with 0.5% tetracaine 10. Soliman et al .…”

Section: Discussionmentioning

confidence: 99%

A single drop of 0.5% proparacaine hydrochloride for uncomplicated clear corneal phacoemulsification

Joshi¹

2013

Middle East Afr J Ophthalmol

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“…They used 4% Xylocaine. It was 4.19 ± 2.321 in the study by Tsoumani et al [7]. They used 0.5% tetracaine.…”

Section: Discussionmentioning

confidence: 89%

Efficacy of 2 Drops versus 3 Drops Proparacaine 0.5% Ophthalmic Solution for Phacoemulsification Surgery: A Comparative Study

Natung¹,

Syiem²,

Keditsu³

et al. 2015

OJOph

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Background and Aim: Phacoemulsification surgery with intraocular lens implantation is routinely done under topical anaesthesia in many centres. No comparative study on the efficacy of number of drops of topical anaesthetics effective for phacoemulsification surgery has been done. This study was conducted to compare the efficacy of 2 drops versus 3 drops proparacaine 0.5% ophthalmic solution for phacoemulsification surgery. Methods: Patients with uncomplicated cataract undergoing phacoemulsification surgery were randomised into two groups. Group 1 (n = 53) received 3 drops of proparacaine 0.5% whereas group 2 (n = 47) received 2 drops of the same solution before the start of surgery. All the patients underwent phacoemulsification with foldable intraocular lens implantation. Each patient's subjective experience of pain was measured using a 10 point Visual Analogue Pain Scale (VAS). Patient's cooperation during the surgery was assessed using a 3 point score. Both the evaluating resident doctor and patients were blinded. Results: In group 1, 73.6% patients scored 0, 20.8% scored 1 and 5.7% scored 2 of VAS respectively and in group 2, 89.4%, 6.4%, 4.3% patients scored 0, 1 and 2 of VAS respectively. In patient cooperation, 90.1% and 9.4% patients in group 1 scored 1 and 2 respectively whereas 87.2% and 12.8% patients scored 1 and 2 respectively in group 2. No statistically significant difference in the mean VAS (P = 0.0.55) and patient cooperation score (P = 0.597) was found between the two groups. The mean VAS score was 1.24 ± 0.534 and the mean patient cooperation score was 1.11 ± 0.314. The mean total surgical time was 25.11 ± 2.68 minutes. No additional drops were required for either group. Conclusions: Topical anaesthesia with both 2 drops and 3 drops proparacaine 0.5% ophthalmic solution is effective for phacoemulsification with intraocular lens implantation. Additional T. Natung et al. 95 anaesthesia may be unnecessary in these cases.

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“…5,6 The triple procedure combining endothelial keratoplasty and phacoemulsification and IOL implantation offers multiple advantages over a staged procedure in the correct setting, including reduced cost and faster visual rehabilitation. 1,7,8 A combination of these techniques, namely the new triple procedure and topical anesthesia, yielded excellent outcomes in our retrospective series of patients.…”

Section: Discussionmentioning

confidence: 99%

Topical–intracameral anesthesia without preoperative mydriatic agents for Descemet-stripping automated endothelial keratoplasty and phacoemulsification cataract surgery with intraocular lens implantation

Oberg

Sikder

Jorgensen

et al. 2012

Journal of Cataract and Refractive Surgery

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Tetracaine 0.5% eyedrops with or without lidocaine 2% gel in topical anesthesia for cataract surgery

Cited by 13 publications

References 19 publications

A single drop of 0.5% proparacaine hydrochloride for uncomplicated clear corneal phacoemulsification

A single drop of 0.5% proparacaine hydrochloride for uncomplicated clear corneal phacoemulsification

Efficacy of 2 Drops versus 3 Drops Proparacaine 0.5% Ophthalmic Solution for Phacoemulsification Surgery: A Comparative Study

Topical–intracameral anesthesia without preoperative mydriatic agents for Descemet-stripping automated endothelial keratoplasty and phacoemulsification cataract surgery with intraocular lens implantation

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