The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego 2010
DOI: 10.1210/endo-meetings.2010.part3.or2.or31-6
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Testosterone Reduces Non-Alcoholic Fatty Liver Disease (NAFLD) of Hypogonadism.

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“…Male mice with liverspecific inactivation of the androgen receptor gene exhibit greater liver fat accumulation than wild-type controls (8). Similarly, severe androgen deficiency, induced by surgical orchiectomy, is associated with the development of hepatic steatosis in male mice fed a high-fat diet (19). Testosterone replacement in hypogonadal men has been reported to reduce whole-body and visceral fat and some components of the metabolic syndrome (5)(6)(7).…”
Section: Discussionmentioning
confidence: 99%
“…Male mice with liverspecific inactivation of the androgen receptor gene exhibit greater liver fat accumulation than wild-type controls (8). Similarly, severe androgen deficiency, induced by surgical orchiectomy, is associated with the development of hepatic steatosis in male mice fed a high-fat diet (19). Testosterone replacement in hypogonadal men has been reported to reduce whole-body and visceral fat and some components of the metabolic syndrome (5)(6)(7).…”
Section: Discussionmentioning
confidence: 99%