Testicular torsion is an emergency that causes the reduction of blood flow in the testis and surrounding structures in neonates, children and adolescents owing to the rotation of the spermatic cord around itself (Yilmaz et al., 2015; Lee et al., 2012). Early diagnosis and surgical management are required to prevent infertility and subfertility (Akgur et al., 1993). The incidence in men under 25 years is 1/4,000 (Mansour et al., 2019). Of the patients, 61% are under 21 years of age and have a bimodal age distribution. It peaks in two separate periods: in neonatal patients and those approximately 13 years of age (Kapoor, 2008; Gomes Dde et al., 2015). Interestingly, the frequency of testicular torsion was associated with environmental factors. In winter, especially in December, the frequency of testicular torsion increased (14%) (Lyronis et al., 2009). Testicular torsion should be diagnosed within the first 4-6 hr. Especially if there is complete spermatic cord torsion (i.e. 720-degree rotation), as it causes irreversible ischaemic damage and gonad loss in the testis (Asgari et al., 2006). Despite successful surgical intervention, 40%-60% of testicular atrophy may develop into infertility in the following years (Yildirim et al., 2018). The main pathophysiology of testicular torsion is, after ischaemic injury induced by a torsioned spermatic cord, surgical detorsion causes reperfusion injury due to free oxygen radicals (Anim et al., 2005). Ischaemia-reperfusion (I/R) damage occurs because of the stimulation of an intracellular cascade containing activation of