Testicular neoplasms in adolescents

Thirty‐two sacrococcygeal neoplasms of germ cell origin were assessed with respect to pathology and natural history. There were 20 mature teratomas, four immature teratomas, one embryonal carcinoma and seven mixed teratomatous neoplasms (teratocarcinomas). All but four neoplasms occurred in infants aged 2 years or younger and 23 of these had visible tumor masses at birth. Only one neoplasm which was present at birth as a visible mass recurred metastasized and caused death. Neoplasms that made their appearance sometime after birth were more frequently malignant. Seventy‐eight per cent of the neoplasms occurred in females. The histologic patterns of growth in these germ cell neoplasms were the same as those encountered in the gonads with the exception that no germinomatous or choriocarcinomatous elements were found. Thirty‐eight per cent of the tumors were histologically malignant although not all behaved so clinically. All mature and immature teratomas were clinically benign. Six of seven teratocarcinomas recurred, metastasized and caused the patients' deaths. The one embryonal carcinoma behaved in a very aggressive manner and caused death of the patient 2 months after diagnosis.

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Testicular and paratesticular neoplasms in patients 60 years of age and older

Abell

Holtz

1968

Cancer

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Testicular and paratesticular neoplasms from 50 patients 60 years of age or older were assessed with respect to histologic type, clinical findings and outcome. Neoplasms of germ cell origin comprised 24% of the series; there were ten seminomas and two teratocarcinomas. The seminomas were palpable many months before diagnosis and were larger than the other neoplasms. Only two deaths could be attributed to their dissemination. Both teratocarcinomas metastasized and caused death. There were five gonadal stromal neoplasms (10%), one Sertoli cell tumor, three interstitial cell tumors and one undifferentiated stromal tumor. None of the neoplasms recurred or metastasized. Eleven neoplasms (22%) were of supportive tissue or paratesticular origin and six of these arose from muscle—one leiomyoma, two leiomyosarcomas and three rhabdomyo‐sarcomas. The other tumors were two malignant mesotheliomas, one fibroma, one fibrosarcoma and one carcinoma of the epididymis. The lymphoreticular neoplasms were the most common lesion in this series and presented as primary testicular tumors in 22 patients (44%). In five patients asynchronous tumors appeared in the other testes. All but two neoplasms were reticulum cell sarcomas. All patients for whom survival information was available died with disseminated disease.

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Testicular neoplasms in adolescents

Cited by 18 publications

References 11 publications

Retroperitoneal germinomas (seminomas) without evidence of testicular involvement

Retroperitoneal germinomas (seminomas) without evidence of testicular involvement

Germ cell neoplasms of sacrococcygeal region

Testicular and paratesticular neoplasms in patients 60 years of age and older

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