Testicular and paratesticular neoplasms in patients 60 years of age and older

Abstract

Testicular and paratesticular neoplasms from 50 patients 60 years of age or older were assessed with respect to histologic type, clinical findings and outcome. Neoplasms of germ cell origin comprised 24% of the series; there were ten seminomas and two teratocarcinomas. The seminomas were palpable many months before diagnosis and were larger than the other neoplasms. Only two deaths could be attributed to their dissemination. Both teratocarcinomas metastasized and caused death. There were five gonadal stromal neoplasms (10%), one Sertoli cell tumor, three interstitial cell tumors and one undifferentiated stromal tumor. None of the neoplasms recurred or metastasized. Eleven neoplasms (22%) were of supportive tissue or paratesticular origin and six of these arose from muscle—one leiomyoma, two leiomyosarcomas and three rhabdomyo‐sarcomas. The other tumors were two malignant mesotheliomas, one fibroma, one fibrosarcoma and one carcinoma of the epididymis. The lymphoreticular neoplasms were the most common lesion in this series and presented as primary testicular tumors in 22 patients (44%). In five patients asynchronous tumors appeared in the other testes. All but two neoplasms were reticulum cell sarcomas. All patients for whom survival information was available died with disseminated disease.

Malignant germ cell tumours in the elderly: a histopathological review of 50 cases in men aged 60 years or over

“…9 One previous series deals specifically with testicular tumours in men 60 or over. 10 They are also mentioned en passant as part of larger series. 8,[11][12][13][14] The incidence of malignant germ cell tumours compared to other testicular neoplasms in the elderly is difficult to determine due to differences in classification.…”

Malignant mesothelioma of the tunica vaginalis testis: A case with a predominant sarcomatous component

“…MM that occur in the tunica vaginalis testis are rare and account for only 0.3−5% of all MM 1–3 . To our knowledge only 84 cases in the English literature have been diagnosed as MM of the tunica vaginalis testis 7–13 . In general, MM of the tunica vaginalis testis has an epithelial component and is occasionally biphasic 11,12 .…”

Primary testicular mucinous neoplasms: case report and literature review

“…4,13 Of the 15 patients with tumours not considered "overtly-malignant," none were reported to have developed recurrence or metastases, and 1 patient died from unrelated causes 10 years post-surgery. 15 Overall, considering the 19 cases with follow-up, 17 were disease-free following orchiectomy at various points post-surgery (Table 1). Since all patients received surgical therapy for their respective tumours, the outcome of a purely observational approach to tumour management is unclear.…”

“…Upon reviewing the English literature, we were able to identify 22 cases, not including this present case report. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] The first reported case to our knowledge was by Kellert in 1959 who described a mucinous cystadenoma in the paratestis of an 11-year-old boy. 2 It was accompanied by an oviduct-like structure and presumed to have arisen from occult and unidentified ovarian tissue.…”