1999
DOI: 10.1016/s0022-5347(05)68649-1
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Testicular Microlithiasis is Associated With Testicular Pathology

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Cited by 35 publications
(54 citation statements)
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“…Five of these studies did not show interval development of TGCT. [17][18][19][20][21] In 3 studies, interval development of TGCT was documented. In the first study, 63 males were screened with ultrasound and 1 developed a TGCT at 5-year follow-up, 22 and in the other 2 prospective studies, 3 patients developed interval tumours; however, all had co-existing risk factors for TGCT.…”
Section: Discussionmentioning
confidence: 99%
“…Five of these studies did not show interval development of TGCT. [17][18][19][20][21] In 3 studies, interval development of TGCT was documented. In the first study, 63 males were screened with ultrasound and 1 developed a TGCT at 5-year follow-up, 22 and in the other 2 prospective studies, 3 patients developed interval tumours; however, all had co-existing risk factors for TGCT.…”
Section: Discussionmentioning
confidence: 99%
“…17,18 The calcifications arise from degeneration of the cells lining the seminiferous tubules. The ultrasonographic appearance with the use of a high-frequency transducer is that of multiple diffuse echogenic foci with no acoustic shadowing (Fig.…”
Section: Microlithiasismentioning
confidence: 99%
“…Studies show that between 1.3% and 6.2% of people with infertility have testicular microlithiasis; 6.7% of patients with cryptorchidism have testicular microlithiasis; and tumors are found in up to 44% of people with microlithiasis, the most common of which is seminoma. 13,17,19,20 The best method for diagnosis and management of microlithiasis is undecided. The options include serial scrotal ultrasonography, serial physical examinations, serial tumor marker screening, and biopsy.…”
Section: Microlithiasismentioning
confidence: 99%
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“…The typical presentation of TM is diffuse calcification (consisting of hydroxyapatite crystals surrounded by layers of collagen fibers) in the seminiferous tubules. There is evidence that TM is a precursor of testicular germ cell tumors 1,2 and that it is associated with infertility 3 . However, it remains unknown whether these are true cause-and-effect relationships or just incidental findings.…”
Section: Introductionmentioning
confidence: 99%