Testicular germ cell tumors. A review of 10 years' experience

Abstract

Experience with 200 cases of testicular tumors seen over a period of 10 years has been presented. Modes of presentation, response to treatment, and patterns of failure have been analyzed in 186 cases of germ cell tumors. The role of radiation in the overall management of seminomas is reaffirmed, and the need for adjuvant radiation to the supraclavicular region and mediastinum is demonstrated in Stage II cases of seminoma. Results of treatment with radiation alone or combined with chemotherapy were not encouraging in nonseminomas in the current series. The advantages of an aggressive multimodal approach with judicious combination of surgery, radiation treatment, and combination chemotherapy have been discussed, with review of relevant literature.

Clinical profile and problems of management of 108 cases of germ cell tumours of testis at Institute Rotary Cancer Hospital, All India Institute of Medical Sciences New Delhi 1985-1990

“…The data for the group as a whole is provided in Figure 5. (Grover et al, 1985). Testicular tumours form about 1% of all tumours registered at IRCH.…”

Metachronous Testicular Germ-cell Tumors: The Importance of a Long-Term Follow-up

“…Testicular cancer is an uncommon disease, representing 1 to 2% of all male cancers, in spite of being the most common malignancy among the youth [ 1 , 2 ]. There are several risk factors for developing a testicular germ cell tumor (TGCT), such as infertility, cryptorchism, microcalcifications and genetic predisposition.…”