Testicular and epididymal percutaneous sperm aspiration in men with either obstructive or nonobstructive azoospermia

Levine, Laurence A.; Dimitriou, Robert J.; Fakouri, Bejan

doi:10.1016/s0090-4295(03)00374-1

Cited by 33 publications

(21 citation statements)

References 17 publications

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“…ICSI with spermatozoa retrieved from the epididymis or testes has been performed for more than 10 years [14]. Studies on day 2-3 transfer have shown good results as compared to traditional IVF, with clinical pregnancy rates in general between 30-40% with multiple embryo transfer [15][16][17]. Small differences have been found between PESA and TESE.…”

Section: Discussionmentioning

confidence: 99%

Single blastocyst transfer after ICSI from ejaculate spermatozoa, percutaneous epididymal sperm aspiration (PESA) or testicular sperm extraction (TESE)

Nilsson

Waldenström

Engström

et al. 2007

J Assist Reprod Genet

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Purpose: To investigate the outcome of IVF following intracytoplasmic sperm injection (ICSI) from ejaculate, percutaneous epididymal sperm aspiration (PESA) and testicular sperm extraction (TESE), with subsequent blastocyst culture and single blastocyst transfer.Methods: Single blastocyst transfer was performed after ejaculate ICSI (oligozoospermia) in 587 patients, TESE/ PESA (azoospermia) in 31 patients, and standard IVF in 680 women.Results: There were only minor differences in IVF characteristics between the standard IVF and the PESA-TESE couples. Couples where ejaculate ICSI were performed seemed to represent a slightly poorer prognostic group. A viable fetus after the 12th gestational week, i.e. ongoing pregnancy, was present in 41.4% after ICSI/ET, 51.6% after PESA-TESE/ET and in 40.4% after standard IVF/ET (no significant differences).Conclusion: Single blastocyst transfer after ejaculate ICSI or after PESA/TESE appears to give similar results as conventional IVF blastocyst culture.

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Section: Discussionmentioning

confidence: 99%

Single blastocyst transfer after ICSI from ejaculate spermatozoa, percutaneous epididymal sperm aspiration (PESA) or testicular sperm extraction (TESE)

Nilsson

Waldenström

Engström

et al. 2007

J Assist Reprod Genet

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“…PESA is a safe and effective technique of sperm retrieval and reports show that successful outcomes in terms of fertilization, embryo development and pregnancy rates can be obtained particularly in cases of nonobstructive azoospermia [9,10] as the one here described. Our case of successful combination of PESA, slow-freezing and vitrification techniques expands the possibilities of positive outcomes within a single treatment cycle, diminishing costs and unwanted repeated ovarian stimulations and oocyte-pick-ups.…”

Section: Discussionmentioning

confidence: 78%

Successful pregnancy after recryopreservation by vitrification of one blastocyst developed from a frozen embryo obtained by PESA: case report

Bös-Mikich

Ferreira²,

Höher³

et al. 2011

J Assist Reprod Genet

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“…MESA and open TeSE are commonly used methods of sperm retrieval, despite reports of less invasive methods, such as aspiration and the use of cutting needle biopsies [8,9] . MESA has the additional potential benefit of simultaneous vasal reconstruction.…”

Section: Discussionmentioning

confidence: 99%

“…Open TeSE is commonly performed in azoospermic males, and has very high rates of successful retrieval in obstructive azoospermia [7] . Other less invasive techniques have also been used to extract testicular sperm, such as TeSA and percutaneous needle biopsies [8,9] . ICSI with testicular spermatozoa recovered by TeSA has been shown to yield results comparable to those using both PESA [8] and open biopsy, although the sperm retrieval rate is not as high in TeSA as by open TeSE [10] .…”

Section: Introductionmentioning

confidence: 99%

“…Other less invasive techniques have also been used to extract testicular sperm, such as TeSA and percutaneous needle biopsies [8,9] . ICSI with testicular spermatozoa recovered by TeSA has been shown to yield results comparable to those using both PESA [8] and open biopsy, although the sperm retrieval rate is not as high in TeSA as by open TeSE [10] . Others [11] have advocated the use of MESA in such individuals, as there is a high rate of retrieval and a low incidence of damage and subsequent scarring.…”

Section: Introductionmentioning

confidence: 99%

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Percutaneous Sperm Retrieval in Secondary Azoospermia

Bromage

Falconer²,

Lieberman³

et al. 2008

Urol Int

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Introduction: Males presenting for assisted reproduction after vasectomy have a high chance of normal spermatogenesis and of successful surgical sperm retrieval. We aimed to evaluate simple percutaneous methods of retrieving sperm for intracytoplasmic sperm injection in males with secondary azoospermia due to previous vasectomy. Patients and Methods: We analyzed a series of post-vasectomy males who presented for sperm retrieval between 1999 and 2005 and who were not being considered for vasal reconstruction as their primary method of re-establishing their fertility. Results: All 132 men had sperm retrieved successfully, 97% with percutaneous methods. In seventy-five percent of the couples intracytoplasmic sperm injection was done, with a total number of 184 cycles being performed. The clinical pregnancy and live birth rates were 25 and 24%, respectively. There were no significant scrotal haematomas, and only 2 patients had postoperative pain after percutaneous sperm retrieval that required analgesia for more than 2 days. Conclusion: We have shown that percutaneous sperm retrieval, where normal spermatogenesis is assumed, is successful in all men following vasectomy. Percutaneous methods of retrieving epididymal or testicular sperm are inexpensive, simple and could replace open techniques in men who are not considering vasal reconstruction following vasectomy.

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Testicular and epididymal percutaneous sperm aspiration in men with either obstructive or nonobstructive azoospermia

Cited by 33 publications

References 17 publications

Single blastocyst transfer after ICSI from ejaculate spermatozoa, percutaneous epididymal sperm aspiration (PESA) or testicular sperm extraction (TESE)

Single blastocyst transfer after ICSI from ejaculate spermatozoa, percutaneous epididymal sperm aspiration (PESA) or testicular sperm extraction (TESE)

Successful pregnancy after recryopreservation by vitrification of one blastocyst developed from a frozen embryo obtained by PESA: case report

Percutaneous Sperm Retrieval in Secondary Azoospermia

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