Terpenoids from Turraeanthus species

Abstract

Chemical investigation of the root bark of Turraeanthus mannii and the stem of T. longipes resulted in the isolation of two new diterpenes, 13-methyl-labda-8(17)-en-15-oic acid (1) and 13-(hydroxymethyl)-14-hydroxy-ent-labda-8(17)-en-15-oic acid (2), along with two known diterpenes, 19-hydroxy-ent-labda-8(17),13-dien-15,16-olide (3) and 19-acetoxy-ent-labda-8(17),13dien-15,16-olide (4), and the phytosterol, stigmasterol. The structure elucidation of the new compounds has been achieved using spectroscopic techniques.

Diterpenoids of terrestrial origin

“…28 The latter is used in traditional Chinese medicine for the treatment of stomach problems. Turreanthus species (Meliaceae) which are better known as sources of limonoid triterpenes, have also afforded 29,30 labdanes including some dimeric compounds. Labdanes from these plants have shown anti-plasmodial activity.…”