Terpenoids from Achillea clypeolata

In vitro antimicrobial activity of extracts of four Achillea species: The composition of Achillea clavennae L. (Asteraceae) extract

“…Both rupicolin A and B have been previously isolated from Achillea setacea (Zitterl-Eglseer et al, 1991), Achillea crithmifolia (Milosavljević et al, 1991), Achillea clypeolata (Todorova et al, 1998), Achillea chrysocoma and Achillea coarctata (Todorova and Tsankova, 2001). The occurrence of rupicolins in many species of this genus suggests that it might be a good taxonomical marker for the genus Achillea.…”

“…Presented data concerning the composition of the extract lead to the conclusion that Achillea clavennae is a typical representative of Achillea genus (Todorova et al, 1998).…”

“…The occurrence of rupicolins in many species of this genus suggests that it might be a good taxonomical marker for the genus Achillea. Besides the 1␣-peroxides of rupicolins whose occurrence is restricted in this genus to Achillea setacea (Zitterl-Eglseer et al, 1991), Achillea clypeolata (Todorova et al, 1998) and now Achillea clavennae, other derivatives of rupicolins like 8-deoxyrupicolin (Todorova and Tsankova, 2001) and 3␣,4␣-epoxyrupicolin (Todorova et al, 1998) are also known to be constituents of Achillea species. Compounds 3, 4, 5 and 6 have been isolated from this species for the first time.…”

Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review

“…A sesquiterpene alcohol: Eudesm-4(15)-em-3α,7α, 11-triol + two sesquiterpene lactones: Guaianolides 3α,4α-epoxyrupicolin-A and 3α,4α-epoxyrupicolin-B (Todorova et al, 1998) A. clypeolata Sm.…”

Composition and antibacterial activity ofAchillea clypeolata essential oil

“…[4][5][6] The essential oil from specimens of A. clypeolata, grown from seed in the botanical garden in Turin, Italy, was investigated by Maffei et al 7 To the best of our knowledge, the essential oil composition of the wild-growing population of A. clypeolata and its antibacterial activity have not been investigated so far. …”