Terminology in surface microscopy

Bahmer, Friedrich A.; Fritsch, Peter; Kreusch, J.; Pehamberger, Hubert; Röhrer, Christian; Schindera, Ingo; Smolle, Josef; Soyer, H. P.; Stolz, Wilhelm

doi:10.1016/s0190-9622(08)80916-4

Cited by 141 publications

(90 citation statements)

References 11 publications

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“…[10][11][12][13] This patchy distribution is a variation of the reticular pattern in which the presence of several small, isolated areas without pigment network leads to multifocal hypopigmentation. Another variation of the reticular type is characterized by multifocal zones of prominent, dark-brown to black pigmented network structures in a patchy distribution.…”

Section: Methodsmentioning

confidence: 99%

Dermoscopic Classification of Atypical Melanocytic Nevi (Clark Nevi)

Hofmann‐Wellenhof

Blum²,

Wolf³

et al. 2001

Arch Dermatol

126

133

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To create a dermoscopic classification of atypical melanocytic nevi (Clark nevi) and to investigate whether individuals bear a predominant type.Design: Digital dermoscopic images of Clark nevi were classified according to structural features, ie, reticular, globular, or homogeneous patterns or combinations of these types. The nevi were also characterized as central hypopigmented or hyperpigmented, eccentric peripheral hypopigmented or hyperpigmented, or multifocal hypopigmented or hyperpigmented. Setting: Two pigmented skin lesion clinics. Patients: We examined 829 Clark nevi on 23 individuals. Main Outcome Measure: A reliable dermoscopic classification of Clark nevi and frequency of different dermoscopic types.

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Section: Methodsmentioning

confidence: 99%

Dermoscopic Classification of Atypical Melanocytic Nevi (Clark Nevi)

Hofmann‐Wellenhof

Blum²,

Wolf³

et al. 2001

Arch Dermatol

126

133

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“…39,40 Many variables related to ELM patterns, the objective value and reproducibility of which are dubious, are today used for the differential diagnosis of PSL. 20 The normal descriptive criteria for melanoma (eg, radial streaming, pseudopods, gray-blue veil) or even benign PSL (regular pigment network) are already complex to quantify, without the further complication of ELM patterns found in both types of lesion but disposed in different ways (eg, pigment network, brown globules, black dots). In such cases, extremely subjective definitions such as "uniform size regularly arranged" or "variable size regularly arranged" or even "uniform size irregularly arranged" instead of "variable size irregularly arranged," have been used.…”

Section: Commentmentioning

confidence: 99%

“…Moreover, for some ELM features, it is not their presence or disposition that is the diagnostic indicator, but rather the extent to which they manifest in a PSL with respect to other morphologic characteristics of the lesion itself and the surrounding skin. 20 Problems such as these made it necessary to use methods such as DDA by which images can be transformed into numbers. 22,23,26 Then algorithms can be designed to obtain objective measurements from unambiguous diagnostic characteristics in line with the main ELM features so far recognized.…”

Section: Commentmentioning

confidence: 99%

Digital Dermoscopy Analysis for the Differentiation of Atypical Nevi and Early Melanoma

Andreassi¹,

Perotti²,

Rubegni³

et al. 1999

Arch Dermatol

125

102

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Objectives: To use a digital dermoscopy analyzer with a series of "borderline" pigmentary skin lesions (ie, clinically atypical nevi and early melanoma) to find correlation between the studied variables and to determine their discriminating power with respect to histological diagnosis.Design: A total of 147 pigmentary skin lesions were histologically examined by 3 experienced dermatopathologists and identified as nevi (n = 90) and melanomas (n = 57). The system evaluated 36 variables to be studied as possible discriminant variables, grouped into 4 categories: geometries, colors, textures, and islands of color.Setting: University medical department.Patients: A sample of patients with excised pigmen-tary skin lesions (nevi and melanomas).Main Outcome Measures: Sensitivity, specificity, and accuracy of the model for evaluating "borderline" pigmentary skin lesions.Results: After multivariate stepwise discriminant analysis, only 13 variables were selected to compute the canonical discriminant function. Conclusion:The present method made it possible to determine which objective variables are important for distinguishing atypical benign pigmentary skin lesions and early melanoma.

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“…In 1989, a Consensus Meeting held by the Committee on Analytical Morphology of the Arbeitsgemeinschaft Dermatologische Forschung in Hamburg provided a new stand ardized terminology of features and terms in dermoscopy in order to be applied to further studies in this field and to bet ter communicate this method to the clinical dermatologist [26,27], In this study, the validity of various dermoscopic fea tures proposed by the Consensus Meeting for detecting melanoma was evaluated based on thorough dermoscopic examination of 159 pigmented skin tumors including 65 melanomas.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Reliability of Dermoscopic Criteria for Detecting Malignant Melanoma

et al. 1995

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Background: Recently a new standardized terminology in dermoscopy has been provided by a Consensus Meeting held by the Committee on Analytical Morphology of the Arbeitsgemeinschaft Dermatologische Forschung in Hamburg in order to be applied to further studies in this field. Objective: In this study on 159 pigmented skin tumors including 65 melanomas, the validity of various dermoscopic criteria proposed by the Consensus Meeting for detecting melanoma was evaluated. Methods: In each lesion, a detailed clinical and dermoscopic examination, photographic documentation of the clinical and dermoscopic appearance, surgical excision and histopathologic evaluation were performed. Statistical analyses including χ² statistics, logistic regression analysis and CART (classification and regression tree) analysis were applied. Results: The diagnosis of melanoma using dermoscopy could be obtained easily, if combinations of the following criteria were observed: whitish veil, pigment network alterations (e.g. irregular pigment network, narrow pigment network, broad pigment network), irregular extensions, black dots and gray-blue areas. Interestingly, however, clinical and dermoscopic examination to detect melanomas yielded the same results, namely a sensitivity of 94%. The combined use of both methods led to an increase in the diagnostic sensitivity of 95%, whereas the combination of clinical and dermoscopic examination with logistic regression analysis of dermoscopic criteria enabled us to detect all 65 melanomas in our data set, thus providing a sensitivity of 100%. Furthermore, an algorithm for the classification of melanoma based on the evaluation of dermoscopic criteria has been constructed by CART analysis showing that the presence of a whitish veil in combination with a pigment network inevitably indicates melanoma. Conclusion: The validity of the various dermoscopic criteria set forth by the Consensus Meeting could be demonstrated as some criteria (e.g. whitish veil, irregular pigment network, irregular extensions) were observed with a significant higher frequency in melanomas.

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Terminology in surface microscopy

Cited by 141 publications

References 11 publications

Dermoscopic Classification of Atypical Melanocytic Nevi (Clark Nevi)

Dermoscopic Classification of Atypical Melanocytic Nevi (Clark Nevi)

Digital Dermoscopy Analysis for the Differentiation of Atypical Nevi and Early Melanoma

Diagnostic Reliability of Dermoscopic Criteria for Detecting Malignant Melanoma

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