Termination of second-trimester pregnancy by mifepristone combined with misoprostol versus intra-amniotic injection of ethacridine lactate (Rivanol®): a systematic review of Chinese trials

Uterine arterial embolization to assist induction of labor among patients with complete placenta previa

“…For example, two women had formed abundant collateral circulation, making it hard to avoid induction failure. In addition, ethacridine lactate has a reported failure rate of 7.4%-20.4% [20].…”

Effects of prophylactic uterine artery embolization on second‐trimester induced abortions in patients with placenta previa

“…Placenta previa is usually regarded as an obstetric emergency because of the high risks of prepartum, intrapartum, and postpartum hemorrhage, hysterectomy, and other refractory adverse events. 5 These medications are the most commonly used medications to terminate a second-trimester pregnancy in the USA. 4 Currently, different methods are used for the termination of a midtrimester pregnancy in different countries.…”

“…11 Given its ability to effectively and rapidly reduce the blood flow of the uterus, UAE has subsequently been used to control postpartum hemorrhage and reduce the bleeding risks associated with cervical varices and cervical pregnancies. 5,7,9,16,17 The present retrospective cohort study was performed to explore whether prophylactic UAE has differential effects on patients with different types of placenta previa (partial and complete) when terminating midtrimester pregnancies. [12][13][14][15] However, the number of patients with placenta previa who request an induced abortion in the second trimester is very limited.…”

“…In comparison with medication used routinely in China-such as ethacridine lactate (in use since 1970)-mifepristone and misoprostol are associated with higher success rates and a shorter duration of labor but have increased gastrointestinal adverse effects. 5 These medications are the most commonly used medications to terminate a second-trimester pregnancy in the USA. 6 In the last 5 years, the use of mifepristone combined with ethacridine lactate has become popular because this combination could improve the outcomes of second-trimester induced abortion compared with ethacridine lactate alone, including for patients with low placentation.…”

“…Consequently, it is difficult for researchers to collect adequate data for relevant studies and the development of UAE as a treatment approach in the context of midtrimester induced abortions in the presence of placenta previa is tardy. 5,7,9,16,17 The present retrospective cohort study was performed to explore whether prophylactic UAE has differential effects on patients with different types of placenta previa (partial and complete) when terminating midtrimester pregnancies.…”