Abstract:Repeated administration is generally necessary t o terminate pregnancy with the last generation of E analogues now in increasing use. In the present study degree of absorption, effect on uterine contractility, and clinical efficacy of a new slow release vaginal device containing between 0.75 t o 2.0 mg 16,16-dimethyltrans-A2 PGEl methyl ester is described. The study included 26 late second trimester patients (15th t o 24th week) and 22 early second trimester patients (12th to 14th week) admitted to the hospita… Show more
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