Terminalia arjuna: A Potential Ayurvedic Cardio Tonic

Thakur, Shifali; Kaurav, Hemlata; Chaudhary, Gitika

doi:10.31033/ijrasb.8.2.30

Cited by 10 publications

(4 citation statements)

References 37 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a blank, a double beam spectrophotometer was used with phosphate buffer (pH 7.4). A graph was plotted between absorbance (y-axis) and concentration (x-axis) 12 .…”

Section: Preparation Of Calibration Curve In Pbs With Ph 74mentioning

confidence: 99%

Untitled

2023

IJPSR

View full text Add to dashboard Cite

Hydrophobic medications that are taken orally having poor bioavailability due to permeability issues. They experience a chemical and enzymatic breakdown in the digestive system and exhibit a significant amount of hepatic first-pass metabolism. Similar obstacles prevent the development of effective therapeutic molecule delivery systems and the discovery of new drugs. It has been revealing that curcumin, a key active lipophilic constituent of Curcuma longa (Zingiberaceae), has a variety of pharmacological properties, including cholagogues, anticancer, and antiinflammatory properties. Based on its organoleptic characteristics, solubility, loss on drying, partition coefficient, infrared spectroscopy, and differential scanning calorimetry, Curcumin was physically and chemically characterized. The drug sample Curcumin was found to be genuine and pure based on the tests. For the purpose of determining in-vitro release and permeation study, an analytical method utilizing RP-HPLC was created and validated. Ionic gelation was used to create chitosan nanoparticles. The study includes the evaluation of various processing conditions, including surface morphology, particle size, particle size distribution, surface charge, percentage yield, entrapment efficiency, and drug loading, as well as ex-vivo permeation studies and in-vitro release models. For Curcumin-nanoparticles, the impact of drug concentration on particle size, polydispersibility index, entrapment efficiency, and loading capacity was optimized. It was found that as the drug: polymer ratio is raised; the average size of curcumin-loaded nanoparticles grows. As per ICH guidelines, the formulation's stability study was also carried out. INTRODUCTION:Curcumin: Turmeric is generated from curcumin (Curcuma longa-Haldi). Curcumin, like many herbal therapeutic compounds, was first ingested as a portion of food before being shown to have a significant pharmacological effect.

show abstract

“…As a blank, a double beam spectrophotometer was used with phosphate buffer (pH 7.4). A graph was plotted between absorbance (y-axis) and concentration (x-axis) 12 .…”

Section: Preparation Of Calibration Curve In Pbs With Ph 74mentioning

confidence: 99%

Untitled

2023

IJPSR

View full text Add to dashboard Cite

show abstract

“…exerting significant inotropic and hypotensive effects increases coronary artery flow and protects myocardium against ischemic damage. It has also been detected to have mild diuretic, antithrombotic, prostaglandin E2 enhancing and hypolipidaemic activity 31,32 .…”

Section: Informant Consensus Factor (Icf)mentioning

confidence: 99%

Untitled

2022

IJPSR

View full text Add to dashboard Cite

Due to plentiful wild plant diversity, poor road conditions to connect modern medical facilities, and age-old folk knowledge on medicinal plants, the tribal communities of Dhemaji District, Assam, India, still practice traditional plant-based therapy in the management of primary healthcare. The present investigation aims to represent the ethnobotanical knowledge of different ethnic community peoples of the Nilakh-Sripani area, a fringe area laying the Assam-Arunachal border. The ethnobotanical field survey (2018-2020) was carried out based on formal and informal semi-structured questionnaires with village headmen, traditional healers, and well-educated persons from 11 villages belonging to Nilakh and Sripanigaon panchayat. Analysis of the demographic profile of informants, local names of plants, parts used, used in ailments, preparation and route of administration was investigated during the survey. The documented data were also quantitatively analyzed by using standard ethnobotanical parameters like Use Value (UV), Fidelity Level (FL) and Informant Consensus Factor (ICF). A total of 102 plant species belonging to 57 families were recorded. During the time of the study, 33 plant species having new ethnobotanical potential were recorded. Besides the uses of plant species in different human ailment categories, 8 plant species are reported in managing livestock diseases especially in poultries, pigs and cattle, and 2 species used as a bio-pesticide in the study area. The study further should be helpful for the valid discovery of a new active pharmaceutical ingredient (API) or drug formulation from natural origin. INTRODUCTION:In India, different tribal community people use more than 8000 medicinal plant species and approximately 25,000 folk medicine-based formulations of their traditional healthcare system 1 . The majority tribal community peoples of entire North-East India, i.e., more than 200 tribes of different ethnic groups, are inhabited in the forest ecosystem and have their sociocultural patterns, tradition, and specific food habits 2 .

show abstract

“…Ancient Indian physicians used the powdered bark of the arjuna tree to treat cardiovascular conditions like angina and "hritshool." Terminalia arjuna, a member of the Combretaceae family, is known locally as Arjuna [3]. As per Charaka Samhita; (Charaka Samhita -Sutra Sthana -ShadvirechanashatashritiyaAdhyaya).…”

Section: Introductionmentioning

confidence: 99%

Chromatographic evaluation of Safranal and Ellagic Acid in Ayurvedic Tea Formulation and its major Ingredients

Meena,

Kumar,

Kamra

et al. 2024

Preprint

View full text Add to dashboard Cite

India is blessed with an extensive variety of plants, trees, shrubs, and herbs that are utilized in the traditional Indian medical system and have been reported to have excellent therapeutic effects in treating ailments. Historically, medicinal plants have been a primary source of compounds used in medicine to treat illnesses. In the indigenous medical system, Terminalia arjuna and Crocus sativusare the most beneficial and well-recognized medicinal plants for treating a wide range of serious illnesses. The goal of this study is thedevelopment of comparative chromatographic profiles ofAyurvedic tea formulation and its major ingredients for identification, and quantitative estimation of concerned PRS/Markers using HPTLC and HPLC. In this study, we have done HPTLC Fingerprint profiling of Ayurvedic tea formulation, Terminalia arjuna, Crocus sativus, Ellagic acid and Safranal.Safranal and Ellagic acid reference standards were visible in test solution of Crocus sativus extract, Terminalia arjuna and Ayurvedic tea formulation respectively and found comparable under UV light and after derivatization with derivatizing reagent. The quantification of Terminalia arjuna and Crocus sativus in formulation was done through HPLC. The quantitative evaluation of Safranal present in Ayurvedic tea formulation and Crocus sativus was 0.0330% and 0.1041% respectively. The quantitative evaluation of Ellagic acid present in Terminalia arjuna,stem bark and Ayurvedic tea formulation was 0.2814% and 0.1293% respectively.

show abstract

Terminalia arjuna: A Potential Ayurvedic Cardio Tonic

Cited by 10 publications

References 37 publications

Untitled

Untitled

Untitled

Chromatographic evaluation of Safranal and Ellagic Acid in Ayurvedic Tea Formulation and its major Ingredients

Contact Info

Product

Resources

About